Topical oxygen therapy has come of age and the evidence supporting its efficacy in healing chronic DFUs can no longer be disputed. ++
Oxygen plays a vital role in healing
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promotes growth factor
cell proliferation &
Oxygen is essential during neutrophil or macrophage respiratory burst, producing reactive oxygen species (ROS) which are extremely important in microbial and debris clearance. ++
Angiogenesis and Revascularisation
Rate and quality of blood vessels affected by oxygen levels, supplemental oxygen accelerates blood vessel growth.++
Cell Proliferation &
Delivering low flow oxygen to a diabetic wound has been shown to increase the rate of wound closure, by as much as 69%. ++
Collagen acts as the structural scaffold of the skin. Higher oxygen concentrations have been found to increase both the amount of collagen production and its tensile strength. ++
Promotes growth factor signalling transduction
Promotion of ROS essential for the signalling processes of growth factors and processes such as angiogenesis and extracellular matrix formation. ++ ++
can improve healing
Supplementary oxygen can help at any phase of healing
NATROX® O2 offers the following benefits:
Generates and delivers pure humidified oxygen directly to wounds 24/7. Continuous flow ensures an oxygen-rich environment
Easy to use
Compatible with most standard care treatments.
Supports patient compliance
Ease of use and portability means minimal disruption to patients’ lifestyle, thus supporting compliance.
Works together with existing therapies, across all patient groups and care settings.
Proven clinical efficacy
71% greater healing rates compared to SOC alone.++ Many clinical studies demonstrate the efficacy of healing with NATROX® O2.
Quick dressing changes and minimum debridement required, freeing up time.
No out-of-hour service or support required. Ability for patients to self-manage.
90% patient satisfaction scores++, improves compliance.
Randomized Control Trial (RCT) on non-healing diabetic foot ulcers
Topical oxygen therapy improved healing of even advanced (Texas Grade III) DFUs, or wounds open up to 88 weeks.++
Assessing if NATROX® O2 is right for your patient
How to apply NATROX® O2
It is important to read the Instruction for Use (IFU) booklet supplied with the device.
Prior to application, remove all old dressings and cleanse the wound, if necessary, in accordance with local policies.
Using an aseptic technique, remove the ODS from its packaging.
Apply directly to the wound bed. Remember to consider the positioning of the tubing for optimum patient comfort. You can position the tube in any direction and secure with tape, if necessary.
Cover the ODS with a suitable absorbent dressing. It is important to seal around the dressing edge to capture the oxygen produced underneath. Do so either use a dressing with an adhesive border, cover with a bandage, or secure the edge with adhesive tape.
If there is a lot of deformity or swelling around the wound, rotating the dressing to a diamond shape can aid conformity.
Once you have secured the dressing, slide a fully charged battery into the device. There is no 'on/off' switch. Simply inserting the battery will automatically start the device working.
Within about 30-seconds, you will see the green light flashing. This indicates oxygen is now flowing.
Connect the ODS to the OG using the twist and lock connector. Be careful not to overtighten.
Change the ODS whenever you change the secondary dressing. However, the ODS needs to be changed at least once a week.
Studies show patients with a chronic wound have a 71% greater chance of healing using NATROX® than with standard of care alone.++
Topical oxygen therapy can improve both patient outcomes and quality of life.++ See for yourself why NATROX® O2 gets 90% patient satisfaction scores.++
Move forward with NATROX® O2
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