Oxygen plays a vital role in healing

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  • promotes growth factor
    signalling transduction

  • collagen
    synthesis

  • cell proliferation &
    re-epithelialisation

  • angiogenesis and
    revascularisation

  • cell metabolism &
    energy production

  • antibacterial
    activities

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Antibacterial Activities

Oxygen is essential during neutrophil or macrophage respiratory burst, producing reactive oxygen species (ROS) which are extremely important in microbial and debris clearance. ++

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Cell metabolism & energy production

Nearly all cellular processes use energy in the form of adenosine triphosphate (ATP)

Low O2 x Glucose = 2 ATP
High O2 x Glucose = 36 ATP++

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Angiogenesis and Revascularisation

Rate and quality of blood vessels affected by oxygen levels, supplemental oxygen accelerates blood vessel growth.++

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Cell Proliferation &
Re-epithelialisation

Delivering low flow oxygen to a diabetic wound has been shown to increase the rate of wound closure, by as much as 69%. ++

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Collagen synthesis

Collagen acts as the structural scaffold of the skin. Higher oxygen concentrations have been found to increase both the amount of collagen production and its tensile strength. ++

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Promotes growth factor signalling transduction

Promotion of ROS essential for the signalling processes of growth factors and processes such as angiogenesis and extracellular matrix formation. ++ ++

Info i icon

Supplementary oxygen
can improve healing

  • NATROX® Oxygen Wound Therapy delivers continuous pure humidified oxygen to the wound bed.
  • Evidence shows oxygen plays a vital role in enabling wound healing.

Supplementary oxygen can help at any phase of healing

NATROX® O2 offers the following benefits:

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Continuous
oxygen therapy

Generates and delivers pure humidified oxygen directly to wounds 24/7. Continuous flow ensures an oxygen-rich environment

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Easy to use

Compatible with most standard care treatments.

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Supports patient compliance

Ease of use and portability means minimal disruption to patients’ lifestyle, thus supporting compliance.

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Active therapy

Works together with existing therapies, across all patient groups and care settings.

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Proven clinical efficacy

71% greater healing rates compared to SOC alone.++  Many clinical studies demonstrate the efficacy of healing with NATROX® O2.

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Time

Quick dressing changes and minimum debridement required, freeing up time.

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Hassle free

No out-of-hour service or support required. Ability for patients to self-manage.

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Patient satisfaction

90% patient satisfaction scores++, improves compliance.

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Randomized Control Trial (RCT) on non-healing diabetic foot ulcers

Topical oxygen therapy improved healing of even advanced (Texas Grade III) DFUs, wounds open up to 88 weeks.++

Assessing if NATROX® O2 is right for your patient

Does my patient need NATROX® O2?

What to expect when using NATROX® O2?

How to increase
patient compliance

Risk factors
to consider

What are the patient benefits of using NATROX® O2?

How to apply NATROX® O2

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Studies show patients with a chronic wound have a 71% greater chance of healing using NATROX® than with standard of care alone.++

Topical oxygen therapy can improve both patient outcomes and quality of life.++   See for yourself why NATROX® O2 gets 90% patient satisfaction scores.++

Move forward with NATROX® O2

References

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