Generated by All in One SEO v5.0.1.1, this is an llms.txt file, used by LLMs to index the site. # NATROX® Wound Care Innovative wound care technology that transforms lives ## Sitemaps - [XML Sitemap](https://www.natroxwoundcare.com/sitemap.xml): Contains all public & indexable URLs for this website. ## Posts - [News](https://www.natroxwoundcare.com/news/) - NATROX® O₂ advanced wound care news and announcements, clinical evidence, press releases, events, and market updates. Get wound healing insights today. - [Medicare Coverage Update: Proposed LCD for Topical Oxygen Therapy Issued](https://www.natroxwoundcare.com/medicare-coverage-update-proposed-lcd-for-topical-oxygen-therapy-issued/) - Update on Proposed Medicare Coverage Determination for Topical Oxygen Therapy We are pleased to share that the DME Medicare Administrative Contractors (DME MACs) have released the long-awaited proposed Local Coverage Determination (LCD DL33797) addressing Topical Oxygen Therapy (TOT). This represents a significant milestone following the LCD reconsideration process initiated in 2021. The proposed LCD establishes - [New Expert Consensus: Topical Oxygen Therapy in Wound Healing](https://www.natroxwoundcare.com/new-expert-consensus-topical-oxygen-therapy-in-wound-healing/) - The Journal of Wound Care has published a new expert-led consensus on the practical, evidence-based use of topical oxygen therapy (TOT) across chronic wound care. Together, an international group of clinical experts reviewed the substantial evidence on the essential role of oxygen in the wound healing process and acknowledged the growing body of evidence supporting TOT as part of wound protocols to help non-healing wounds progress. They also offered practical guidance on how the therapy can be incorporated into current best practices to improve outcomes and ultimately patients’ lives. - [WHS Grants 'Level I' Recommendation to Topical Oxygen Therapy](https://www.natroxwoundcare.com/whs-grants-level-i-recommendation-to-topical-oxygen-therapy/) - The Wound Healing Society (WHS) has recently increased topical oxygen therapy to 'Level 1' Evidence in its updated DFU treatment guidelines, signifying a significant leap in the field. The WHS publishes guidance for clinicians with the goal of improving patient care. The new guidelines for diabetic foot ulcer (DFU) treatment have been updated since its 2016 publication to reflect new, higher-quality evidence. Highlighted in the new guidelines were two Meta-analyses, which include NATROX® O₂ cTOT RCT data. - [Workshop on the Role of Oxygen in Wound Healing and the NATROX® O2 Oxygen Wound Therapy](https://www.natroxwoundcare.com/workshop-on-the-role-of-oxygen-in-wound-healing-and-the-natrox-oxygen-wound-therapy/) - On Tuesday 27th June 2018, Inotec AMD and Wounds UK hosted a very exciting and content-rich workshop on the role of oxygen in wound healing and the Inotec’s NATROX® Oxygen Wound Therapy. - [NATROX® O₂ Now Available Through NHS Supply Chain & NHS Shared Business Services](https://www.natroxwoundcare.com/natrox-oxygen-wound-therapy-now-available-through-nhs-supply-chain-nhs-shared-business-services/) - Continuous topical oxygen therapy widely available and easier than ever for clinicians to prescribe [Cambridge, UK – 26 January 2022] – Inotec AMD Ltd. is pleased to announce it has been recently added as an approved supplier to the UK’s NHS Supply Chain and NHS Shared Business Services (NHS SBS). Known for its innovative technology in advanced medical devices, Inotec - [NATROX® Wound Care Recognized by CIO Bulletin as a Top MedTech Innovator](https://www.natroxwoundcare.com/natrox-wound-care-recognized-by-cio-bulletin-as-a-top-medtech-innovator/) - We are proud to announce that NATROX® Wound Care has been featured in CIO Bulletin’s October 2025 edition as one of the “Best Medical Device Companies to Watch.” This honor highlights our role in advancing chronic wound healing through innovative, wearable oxygen therapy. Our flagship product, NATROX® O₂ Continuous Topical Oxygen Therapy (cTOT), empowers patients to heal - [The Silicon Review Recognizes NATROX® Wound Care as a Top 5 MedTech Company to Watch in 2025](https://www.natroxwoundcare.com/the-silicon-review-recognizes-natrox-wound-care-as-a-top-5-medtech-company-to-watch-in-2025/) - We are thrilled to announce that NATROX® Wound Care has been named one of the "5 Best MedTech Companies to Watch in 2025" by The Silicon Review. This recognition underscores our commitment to transforming chronic wound care through innovative solutions like our NATROX® O₂ Continuous Topical Oxygen Therapy (cTOT). Our patient-centered approach aims to enhance - [Spartan Medical Partners with NATROX® to Bring Continuous Topical Oxygen Therapy (cTOT) to Veterans & Federal Facilities](https://www.natroxwoundcare.com/spartan-medical-partners-with-natrox-to-bring-continuous-topical-oxygen-therapy-ctot-to-veterans-federal-facilities/) - NATROX® Wound Care, a leading innovator in advanced therapies, is proud to announce a strategic partnership with Spartan Medical, a trusted supplier and contractor of medical technologies for the Federal Government. Together, the companies will broaden access to unique and effective wound care solutions within federal healthcare systems, including the U.S. Department of Veterans Affairs (VA), Department of Defense (DoD), and Indian Health Services (IHS). - [NATROX® Wound Care Announces Vice President of U.S. Sales & Global Marketing](https://www.natroxwoundcare.com/natrox-wound-care-announces-vice-president-of-u-s-sales-global-marketing-2/) - [Cambridge, 21 March 2025] - NATROX® Wound Care, an Inotec AMD company and the leading innovator in continuous topical oxygen therapy (cTOT) for advanced wound care, is pleased to announce the promotion of Nancy Stahulak to Vice President of U.S. Sales & Global Marketing. This strategic appointment underscores the company's commitment to accelerating growth in - [As part of LER Magazine’s (Lower Extremity Review) 15th anniversary celebration, they asked readers to weigh in on the many facets of innovation that have helped improve patient outcomes in lower extremity care.](https://www.natroxwoundcare.com/as-part-of-ler-magazines-lower-extremity-review-15th-anniversary-celebration-they-asked-readers-to-weigh-in-on-the-many-facets-of-innovation-that-have-helped-improve-patient/) - We’re honored to see NATROX® O₂ Continuous Topical Oxygen Therapy on the list (page 35) as it not only improves wound healing outcomes, it also offers an alternative method to pain management, reduces risk of infection, and provides an easy way for patients to receive in-home treatment that doesn’t interrupt their activities of daily living. - [Inotec AMD Appoints Stefanie Brown Hawkins as CFO to Drive Strategic Growth and Innovation](https://www.natroxwoundcare.com/inotec-amd-appoints-stefanie-brown-hawkins-as-cfo-to-drive-strategic-growth-and-innovation/) - Inotec AMD today announced the appointment of Stefanie Brown Hawkins as Chief Financial Officer. Stefanie brings a wealth of experience as she joins Inotec AMD following a successful career having held a number of key finance and strategy leadership positions across Gilead, GlaxoSmithKline and AstraZeneca. - [Inotec Secures $33 Million in Series C Financing to Accelerate US Expansion](https://www.natroxwoundcare.com/inotec-amd-secures-33-million-in-series-c-financing-to-accelerate-us-expansion/) - Inotec AMD, whose product NATROX® O₂ is the leader in continuous topical oxygen therapy (cTOT) for advanced wound care, today announced the successful close of a $33 million Series C financing round. The funding, led by existing internal investors, marks a major milestone in the company’s mission to revolutionize wound management and improve patient outcomes on a global scale. - [NATROX® to Exhibit at SAWC Spring 2023](https://www.natroxwoundcare.com/natrox-to-exhibit-at-sawc-spring-2023/) - Join us in National Harbor, Maryland at SAWC Spring 2023 taking place April 26-30. You can find NATROX® Wound Care at booth 341. Don’t miss the latest clinical evidence on topical oxygen which will be presented at the show by Dr. Aliza Lee, DPM, MS, ABPM, Director of Podiatric Medical Education, Staff Podiatrist and Clinical Research Investigator, Salem VA Medical Center. - [Dr. Windy Cole, DPM Joins NATROX® Wound Care as Director of Global Medical Affairs](https://www.natroxwoundcare.com/dr-windy-cole-dpm-joins-natrox-wound-care-as-director-of-medical-affairs/) - NATROX® Wound Care is excited to announce that Dr. Windy Cole, DPM will join as Director of Global Medical Affairs. She joins at a critical juncture as the company increases product availability worldwide and seeks to develop new solutions to improve chronic wound patient outcomes. Dr. Cole will be responsible for developing and overseeing medical strategy, strengthening strategic partnerships among key opinion leaders (KOLs), and advancing clinical evidence to support industry recognition of advanced wound therapies. “Windy is an outstanding addition,” said Craig Kennedy, NATROX® Wound Care CEO. “She’s been on the forefront of wound research and has dedicated her career to advancing wound care. We first collaborated with Windy as a Principal Investigator (PI) in our clinical trials investigating the impact of topical oxygen therapy on chronic DFUs. Her profound passion for helping others aligns perfectly with our mission to transform patients’ lives.” - [NATROX® Symposium at EWMA 2023](https://www.natroxwoundcare.com/natrox-symposium-at-ewma-2023/) - Join us 3 May at EWMA for a ground breaking symposium. Learn how innovative topical oxygen therapy helps deliver substantial, rapid pain relief and can support an end to opioid use completely. This new therapy is a novel alternative to hyperbaric oxygen therapy (HBOT) in the treatment of chronic wounds, providing an easily accessible, low-cost option for improved wound healing. Featured speakers include Dr. Thomas Serena from the SerenaGroup and Dr. Jakob WIkström from the Karolinska University Hospital in Sweden. - [Raise Healthcare Named UK Distributor for NATROX® Wound Care](https://www.natroxwoundcare.com/raise-healthcare-named-uk-distributor-for-natrox-wound-care/) - We're excited to announce Raise Healthcare as our exclusive distributor in the United Kingdom. Raise Healthcare is a UK-based specialist medical device distributor known for its extensive portfolio of life-changing products. “This partnership brings together Raise Healthcare’s experienced team with NATROX®’s innovative wound care therapy,” said Rajesh Nair, Director for Raise Healthcare. “We invest time and resources to understand the needs of patients so we can provide exceptional products such as NATROX® O₂ that positively impact lives every day.” - [Celebrating Our Success: We Topped the MedTech50 List Again!](https://www.natroxwoundcare.com/celebrating-our-success-we-topped-the-medtech50-list-again/) - We're thrilled to share some exciting news. NATROX® Wound Care has once again secured the prestigious FIRST place in the MedTech50 list, making it TWO consecutive first-place wins for our innovative startup!This remarkable achievement would not have been possible without your unwavering support and belief in our vision. Your votes played a pivotal role in - [New Expert Guidelines from IWGDF Highlight the Growing International Recognition of Topical Oxygen Therapy (TOT) for Diabetic Foot Ulcers](https://www.natroxwoundcare.com/new-expert-guidelines-from-iwgdf-highlight-the-growing-international-recognition-of-topical-oxygen-therapy-tot-for-diabetic-foot-ulcers/) - The International Working Group on the Diabetic Foot (IWGDF) have recently released updated guidelines recommending the use of topical oxygen therapy (TOT) for wound healing. The updated guidelines endorse TOT as an adjunct therapy in the treatment of diabetic foot ulcers (DFUs). With its endorsement by leading experts in the field, this ground-breaking therapy is poised to transform the lives of millions of people worldwide, offering renewed hope for effective healing and improved quality of life. This comprehensive set of recommended DFU interventions, developed by a panel of renowned experts in the field whose mission is to prevent and manage diabetic foot disease, serves as a trusted resource for healthcare professionals worldwide. With its inclusion in the IWGDF guidelines, topical oxygen therapy emerges as a vital tool, poised to revolutionize the management and healing of foot ulcers in individuals with diabetes. - [Introducing NATROX® Wound Care's New Video Series Showing How to Apply NATROX® O₂ ](https://www.natroxwoundcare.com/introducing-natrox-wound-cares-new-video-series-showing-how-to-apply-natrox-o₂/) - Step-by-step guidance on using this effective continuous topical oxygen therapy with minimal training 21 June 2023– Cambridge, UK] - NATROX® Wound Care, a leading provider of advanced wound care solutions, is pleased to announce the launch of an informative video series aimed at demonstrating the quick and easy application of NATROX® O₂ continuous topical oxygen - [Inotec AMD is Expanding its Quality Team](https://www.natroxwoundcare.com/inotec-amd-is-expanding-its-quality-team/) - Join our mission to improve the lives of patients with chronic wounds. We're expanding our Quality team in Waterbeach/Cambridge, UK. We have new, exciting opportunities for Quality Engineers and Document Controllers. Your contribution can increase the reach of our product across the globe. Moreover, you can help transform patients' quality of life. Our growing, enthusiastic - [How wound care clinicians can optimize clinical outcomes and resources](https://www.natroxwoundcare.com/how-wound-care-clinicians-can-optimize-clinical-outcomes-and-resources/) - 12-week study on 8 patients exploring the combined use of NATROX® O₂ with an advanced digital platform using Telehealth to understand the clinical benefits - [Delphi Consensus on Guidelines for the Use of Topical Oxygen](https://www.natroxwoundcare.com/delphi-consensus-on-guidelines-for-the-use-of-topical-oxygen/) - Delphi participants reached a consensus on when to prescribe topical oxygen therapy (TOT). Experts recommend using TOT in diabetic foot ulcers (DFUs) and supported payer reimbursement for this therapy modality. Experts agreed TOT should be considered in the following circumstances: Delayed wound healing Failure of prior therapies Ischemic ulcers Wound types likely to benefit: Diabetic - [NATROX® O₂ Masterclass Guide](https://www.natroxwoundcare.com/natrox-o₂-masterclass-guide/) - A new guide has been published in Wound Masterclass. It provides an overview on NATROX® O₂ and how it works. It covers what wounds are suitable and what wounds are not. It shows the stages of treatment, and also covers the clinical evidence and efficacy, including data on wound size reduction. Download now - [New Study Demonstrates Significantly Increased Healing Rates with NATROX® O₂](https://www.natroxwoundcare.com/new-study-demonstrates-significantly-increased-healing-rates-with-natrox-oxygen-wound-therapy/) - Inotec AMD, manufacturer of NATROX® Oxygen Wound Therapy, is delighted to share newly published randomised controlled trial (RCT) results. The trial involved 145 patients with previously non-healing diabetic foot ulcers (DFUs) and compared the effects of using standard care against a combination of standard care plus NATROX® Oxygen Wound Therapy. Patients completing the therapy experienced 71% greater healing rates and 73% greater reduction in wound size using NATROX®. These results offer hope to patients suffering from chronic wounds. - [Health Technology Wales Guidance Advises Routine Adoption of NATROX® O₂](https://www.natroxwoundcare.com/health-technology-wales-guidance-advises-routine-adoption-of-natrox-o₂/) - Health Technology Wales (HTW) has published Guidance advising the routine adoption of NATROX® O₂ for the treatment of chronic, non-healing and complex diabetic foot ulcers (DFUs). “We have the opportunity right now to reshape the future. We’ve all seen the statistics on diabetes—and frankly, they’re depressing. What motivates our team is seeing the positive impact NATROX® O₂ makes on patients every day. Being included in this Guidance is another step towards shaping a future we can all feel inspired by,” said Kennedy. - [NATROX® O₂ Now Available in South Korea](https://www.natroxwoundcare.com/natrox-o₂-now-available-in-south-korea/) - We are pleased to announce the Ministry of Food & Drug Safety (MFDS) has granted approval to ship and sell our groundbreaking product NATROX® O₂ topical oxygen therapy into South Korea. A newly added NATROX® distribution partner in South Korea, KOVE Inc., was instrumental in getting the product registered in its country. This milestone marks the first time patients in South Korea will access this leading-edge medical device, bringing new hope to those suffering from chronic wounds. “We’re thrilled to introduce NATROX® O₂ to the South Korean market together with our new partner, KOVE,” said Craig Kennedy, CEO of NATROX® Wound Care. “This marks a significant milestone in our journey to revolutionize wound care on a global scale. We’re confident NATROX® O₂ will be a game-changer for wound care in the country.” - [Inotec AMD Moves to Larger Office to Prepare for US Growth](https://www.natroxwoundcare.com/inotec-amd-moves-to-larger-office-to-prepare-for-us-growth/) - Increased Demand of NATROX® O₂ Drives Need to Add Key Employees to Support Customers [Hickory, NC –July 27, 2021] – Inotec AMD Inc. relocated to a new, larger office in Hickory, North Carolina in mid-July. Located near the heart of downtown Hickory, the larger space supports the company’s initiatives to expand its footprint in the US market. - [New Evidence in Support of Topical Oxygen Therapy (TOT)](https://www.natroxwoundcare.com/new-evidence-in-support-of-topical-oxygen-therapy/) - A new publication by the American Diabe­tes Association presents the latest evidence-based therapies for diabetic foot ulcers (DFUs). Contributing authors include heavy hitters such as Andrew Boulton, David Armstrong, Magnus Löndahl, and Robert Frykberg. They review the most recently published evidence-based data concerning topical oxy­gen therapies in addition to looking at future treatment approaches in the development pipeline, as well as the emerging role of wearable technologies. Throughout the compendia, the authors present their view of current and forthcoming treatment options and iden­tify areas worthy of additional research in the years ahead. - [Nancy Stahulak Joins NATROX® Wound Care as VP of Global Marketing](https://www.natroxwoundcare.com/nancy-stahulak-joins-natrox-wound-care-as-vp-of-global-marketing/) - NATROX® Wound Care announces Nancy Stahulak as Vice President (VP) of Global Marketing. She joins the team as it is expanding product access worldwide and expects to continue making inroads towards product reimbursement in the USA. Nancy will be responsible for developing and implementing a global marketing strategy, strengthening the company’s brand position, and generating growth through clinician engagement. “Nancy is a strategic, customer-focused marketing leader with a proven track record for driving top-line growth and long-term market sustainability,” said Craig Kennedy, CEO of NATROX® Wound Care. “She is a perfect fit coming from Medela, as it gives her a solid understanding of the challenges facing the wound care industry and a deep understanding of our customers.” - [New Expert Opinion in Support of Topical Oxygen Therapy (TOT)](https://www.natroxwoundcare.com/new-expert-opinion-in-support-of-topical-oxygen-therapy-tot/) - Experts agree that "topical oxygen therapy has come of age and the evidence supporting its efficacy in healing chronic diabetic foot ulcers can no longer be disputed." - [New poster presented at DFCon 2022 by Dr. Lee](https://www.natroxwoundcare.com/new-poster-presented-at-dfcon-2022-by-dr-lee/) - Managing patients with chronic non-healing wounds is challenging particularly for those in rural communities. This small, pilot study over 12-week study aimed to explore whether NATROX® Oxygen Wound Therapy (cTOT) in conjunction with an advanced digital platform with telehealth capabilities can offer clinical benefits while optimizing the limited clinical resources. During the study, patient-clinician interactions - [NATROX® Symposium at EWMA 2018](https://www.natroxwoundcare.com/natrox-symposium-at-ewma-2018/) - Inotec AMD hosted a well-attended symposium at the 2018 EWMA Conference in Krakow (Poland). The Symposium, chaired by Paul Hayes, focused on the vital role of oxygen in chronic wound healing and the importance of the Inotec’s NATROX® Oxygen Wound Therapy supported by a series of case studies presented by Hanna Kaufman and Thomas Serena. - [NATROX® Symposium at GWC 2018](https://www.natroxwoundcare.com/natrox-symposium-at-gwc-2018/) - NATROX® Symposium achieved an incredible audience with all the sessions being well-received. The Symposium, chaired by Dr Tang, focused of the vital role of oxygen in chronic wound healing and presented some challenging wounds which all benefited from the utilisation of NATROX® Oxygen Wound Therapy. - [NATROX® Symposium at the Philippine Wound Care Society Annual Conference 2019](https://www.natroxwoundcare.com/natrox-symposium-at-the-philippine-wound-care-society-annual-conference-2019/) - NATROX® Oxygen Wound Therapy featured in an exciting and thought-provoking symposium at the Philippine Wound Care Society Annual Conference 2019 in Manila (Philippines). This innovative Symposium was chaired by Dr Harikrishna and focused of the vital role of oxygen in wound healing and potential management options when blood flow is compromised. The symposium included some outstanding Malaysian case studies showing the impact of NATROX® Oxygen Wound Therapy in previously non-healing chronic wounds. - [NATROX® Breakfast Symposium at GWC 2019 in Kuala Lumpur](https://www.natroxwoundcare.com/natrox-breakfast-symposium-at-gwc-2019-in-kuala-lumpur/) - Dr.Thomas Serena, Founder and Medical Director of the SerenaGroups, USA highlights the benefits of continuous topical oxygen therapy along with the importance of early identification of patients with NATROX® - [Inotec AMD hosting a NATROX® Symposium at 2020 World Union of Wound Healing Societies (WUWHS) Conference](https://www.natroxwoundcare.com/inotec-amd-hosting-a-natrox-symposium-at-2020-world-union-of-wound-healing-societies-wuwhs-conference/) - NATROX® Oxygen Wound Therapy will be featured in an exciting symposium at the 2020 World Union of Wound Healing Societies (WUWHS) Conference on Tuesday, 10th March from 12:30pm to 2pm, Conference Hall B. The symposium, chaired by Professor Keith Harding, is titled “NATROX®, A step forward in wound care”. - [NATROX® US Randomized Control Trial (RCT) submitted for publication](https://www.natroxwoundcare.com/natrox-us-randomized-control-trial-rct-submitted-for-publication/) - The NATROX® Oxygen Wound Therapy US Randomized Control Trial (RCT) has now been submitted for publication, following data analysis. The trial focused on non-healing diabetic foot ulcers (DFUs) and primarily evaluated the impact of continuous topical oxygen on healing outcomes when compared to best practice standard of care. With well over 100 patients completing the full 12 week therapy period, this study is expected to become a key paper supporting the use of continuous topical oxygen therapy in non-healing DFUs. - [NATROX® Team Attending EWMA 2022](https://www.natroxwoundcare.com/natrox-team-attending-ewma-2022/) - We are looking forward to attending EWMA taking place 23 - 25 May at the Palais des Congrès in Paris. Stop by to visit us at stand 261 to experience NATROX® Oxygen Wound Therapy and learn how topical oxygen can help at any phase of wound healing. Register for the show: View the floorplan: See you soon in - [Inotec AMD Makes the MedTech50 for Innovative Medical Technology](https://www.natroxwoundcare.com/inotec-amd-makes-the-medtech50-for-innovative-medical-technology/) - Recognised as a Top 50 trailblazer creating original technology for the healthcare and medical sectors [Cambridge, UK – 28 July, 2021] – Inotec AMD, Ltd. is pleased to announce it ranked 34 in the MedTech50, recognised as one of the UK's most innovative medical technology creators for 2021. The award honours companies helping diagnose and treat conditions - [InterMed Medical Appointed Exclusive Distributor in Australia and New Zealand for Inotec](https://www.natroxwoundcare.com/intermed-medical-appointed-exclusive-distributor-in-australia-and-new-zealand-for-inotec/) - Inotec AMD Ltd. announces InterMed Medical will be its exclusive distributor for Australia and New Zealand. On the back of increased demand worldwide, this partnership will expand Inotec’s global reach through InterMed’s extensive wound care market knowledge and enhance InterMed’s portfolio offering. “We’re excited about making NATROX® available to patients in Australia and New Zealand,” says Ben Darling, Country Manager for InterMed Australia. “We have a unique opportunity to transform people’s lives with something as simple as oxygen.” - [Dr. Thomas Serena Joins NATROX® Wound Care Team as Chief Medical Officer](https://www.natroxwoundcare.com/dr-thomas-serena-joins-natrox-wound-care-team-as-chief-medical-officer/) - NATROX® Wound Care is excited to announce the addition of Dr. Thomas Serena, MD FACS FACHM MAPWCA, who joins as Chief Medical Officer (CMO) effective immediately. The internationally recognised expert in the field of wound healing has been the lead or Principal Investigator in over 100 clinical trials. He has a vast knowledge of oxygen therapy and understands its positive impact on chronic wounds. “Having Tom onboard adds tremendous clinical credibility around the wound care benefits of topical oxygen,” said Craig Kennedy, CEO. “Tom will be supporting our strategy to making NATROX® O₂ readily available to all patients, which includes securing USA reimbursement.” - [John Adam Joins NATROX® Wound Care as Chief Operating Officer](https://www.natroxwoundcare.com/john-adam-joins-natrox-as-chief-operating-officer/) - NATROX® Wound Care is pleased to announce the appointment of John Adam to take the role of Chief Operating Officer (COO). He will support the leadership team in executing the company’s vision of transforming the lives of patients suffering from hard-to-heal wounds through innovative technology. John will assume responsibility for manufacturing operations, quality, and product development to optimise the way NATROX® delivers an excellent customer experience to its global client base. - [New study shows substantial pain relief with NATROX® O₂](https://www.natroxwoundcare.com/new-study-shows-substantial-pain-relief-with-natrox-o₂/) - A new study published in the Journal of Wound Care reveals that NATROX® Oxygen Wound Therapy can help relieve pain in hard-to-heal leg ulcers while improving healing rates. A dramatic 76% of patients had "substantial, rapid pain relief" and 69% stopped taking opioids completely. Read the full article on our website: Watch a video summary: - [NATROX® Wound Care Appoints Eminent Wound Care and Biofilm Expert, Dr. Gregory Schultz, as Chief Scientific Officer](https://www.natroxwoundcare.com/natrox-wound-care-appoints-eminent-wound-care-and-biofilm-expert-dr-gregory-schultz-as-chief-scientific-officer/) - “Dr. Schultz is a fantastic addition to our team and adds scientific credibility to our technologies. His knowledge and experience will be invaluable as we continue to grow our innovative oxygen therapy business and develop next-generation technologies aimed at supporting clinicians and empowering patients who suffer from chronic wounds.” - [Small wounds can cause death in diabetes patients](https://www.natroxwoundcare.com/small-wounds-can-cause-death-in-diabetes-patients/) - For people with diabetes a small, undetected foot wound can quickly lead to infection, amputation and even death. Better wound care and new therapies can save lives. - [Inotec AMD Ltd Appoints Craig Kennedy as New CEO](https://www.natroxwoundcare.com/inotec-amd-ltd-appoints-craig-kennedy-as-new-ceo/) - Cambridge-based Inotec AMD Limited is pleased to announce the appointment of Craig Kennedy as its new Chief Executive Officer on 3 March 2018. - [Recent International Inotec team meeting in Cambridge, the home of NATROX® Oxygen Wound Therapy](https://www.natroxwoundcare.com/recent-international-inotec-team-meeting-in-cambridge-the-home-of-natrox-oxygen-wound-therapy/) - With the significant increase in clinical awareness of the benefits of oxygen wound therapy and in particular NATROX® Oxygen Wound Therapy the senior global management team have become very busy people with few opportunities to meet up. However with the addition of Craig Kennedy the new CEO to the team it seemed an ideal opportunity to meet and share success stories across the globe. - [Inotec supporting clinical education](https://www.natroxwoundcare.com/inotec-supporting-clinical-education/) - A great day with our partners in Ireland HC21, at the Tissue Viability Nurses Association of Ireland meeting. Fantastic speakers Dr Georgina Gethin, Julie Stanton and Gail Curran, as well as a very knowledgeable audience, as we introduced the benefits of NATROX® Oxygen Wound Therapy for chronic non-healing wounds. - [Thomas Serena on the role of oxygen therapy in wound care](https://www.natroxwoundcare.com/thomas-serena-on-the-role-of-oxygen-therapy-in-wound-care/) - Thomas Serena, founder of the global healthcare Serena Group , discussed the importance of oxygen therapy in wound care and his work with NATROX® Oxygen Wound Therapy. - [Inotec AMD Limited attended the Frost & Sullivan's 2018 Excellence in Best Practices Awards Banquet in London](https://www.natroxwoundcare.com/inotec-amd-limited-attended-the-frost-sullivans-2018-excellence-in-best-practices-awards-banquet-in-london/) - Cambridge, UK – 12 October 2018 - Cambridge based Inotec AMD has attended the Frost & Sullivan's 2018 Excellence in Best Practices Awards Banquet on the 4th October 2018, at the Royal Garden Hotel in London to receive the prestigious 2018 Product Leadership Award in Chronic Wound Care Management from Frost & Sullivan. - [Inotec AMD Limited signs distributor agreement with AG-Nass, LLC Medical Supply](https://www.natroxwoundcare.com/inotec-amd-limited-signs-distributor-agreement-with-ag-nass-llc-medical-supply/) - Cambridge based Inotec AMD Limited is excited to announce that they have signed a distributor agreement with AG-Nass, LLC Medical Supply Distribution. - [Inotec AMD Limited appoints new Vice President - America](https://www.natroxwoundcare.com/inotec-amd-limited-appoints-new-vice-president-america/) - Cambridge based Inotec AMD Limited is pleased to announce the appointment of Kathy Hohenberger as its new Vice President - America on 10 September 2018. - [Inotec AMD Limited receives the Global 2018 Product Leadership Award in Chronic Wound Care Management from Frost & Sullivan](https://www.natroxwoundcare.com/inotec-amd-limited-receives-the-global-2018-product-leadership-award-in-chronic-wound-care-management-from-frost-sullivan/) - Cambridge, UK – 9 July 2018 - Cambridge based Inotec AMD Limited’s NATROX® Oxygen Wound Therapy has earned the prestigious 2018 Product Leadership Award in Chronic Wound Care Management from Frost & Sullivan. - [Inotec AMD Limited announces the opening of its first office in the US](https://www.natroxwoundcare.com/inotec-amd-limited-announces-the-opening-of-its-first-office-in-the-us/) - Cambridge, UK – May 2018 - Cambridge based Inotec AMD Limited is pleased to announce the opening of its first office in the US. - [NATROX® International Advisory Board Meeting](https://www.natroxwoundcare.com/natrox-international-advisory-board-meeting/) - Inotec AMD Ltd hosted an International Advisory Boarding meeting in Windsor on the 19th September 2019. - [Oxygen research wins 2019 Nobel Prize in Medicine](https://www.natroxwoundcare.com/oxygen-research-wins-2019-nobel-prize-in-medicine/) - Research conducted by 3 scientists into how cells detect and react to oxygen has been awarded the 2019 Nobel Prize in Physiology or Medicine - [Inotec AMD in the Top 10 Wound Care Solutions Providers - 2019](https://www.natroxwoundcare.com/inotec-amd-in-the-top-10-wound-care-solutions-providers-2019/) - Inotec AMD recognized by MedTech Outlook magazine as Top 10 Wound Care Solutions Providers - 2019. Inotec AMD is considered at the forefront of providing expert wound care solutions and services and impacting the marketplace. - [Inotec AMD Announces New Director of Human Resources to Support Global Team](https://www.natroxwoundcare.com/inotec-amd-announces-new-director-of-human-resources-to-support-global-team/) - Sandy Fliri-Marx brings 20 years international expertise to advance corporate expansion plans. Having worked in Senior HR Management for leading biotechnology companies, Fliri-Marx has developed successful HR strategies for organizations of varying sizes with locations across the globe. The role is pivotal for Inotec, a young, growing company currently expanding its workforce to meet increased manufacturing demands. - [Jane Clark, VP Global Marketing & Clinical Affairs, in Top 25 Women Leaders in Medical Devices 2021](https://www.natroxwoundcare.com/jane-clark-vp-global-marketing-and-clinical-affairs-in-the-top-25-women-leaders-in-medical-devices-of-2021/) - Jane Clark, VP Global Marketing and Clinical Affairs has been recognised as one of the Top 25 Women Leaders in Medical Devices of 2021 by The Healthcare Technology Report. According to The Healthcare Technology Report “Jane stood out for her depth of specialized knowledge and overall impact on her organization as well as the medical device field. Jane brings both executive and clinical experience to her current role, including a tenure as a tissue viability specialist within the UK's National Health Service (NHS). - [NATROX® O₂ Wins the “Best Wearable Tech in Health Care" Award](https://www.natroxwoundcare.com/natrox-wins-the-best-wearable-tech-in-health-care-award/) - NATROX® Oxygen Wound Therapy named the best wearable tech in health care by GIANT. The product was selected from a large pool of nominees from a panel of independent judges. The prestigious award recognizes NATROX® for its patient-centricity with key advantages listed as battery power, silent operation, and complete portability. The product fits under normal clothes, resulting in minimal intrusion to patients' lives. - [Inotec AMD Expands Global Headquarter Office in Cambridge, UK](https://www.natroxwoundcare.com/inotec-amd-expands-global-headquarter-office-in-cambridge-uk/) - Inotec AMD expands its global headquarter in Cambridge (UK) - [Craig Kennedy, Inotec AMD, included in the 10 Best Inspiring CEOs of 2020](https://www.natroxwoundcare.com/craig-kennedy-inotec-amd-included-in-the-10-best-inspiring-ceos-of-2020/) - Craig Kennedy, Inotec AMD’s CEO, has been included in the 10 Best Inspiring CEOs of 2020 according to Industry Era. - [Patrick Barron, VP Operations, wins a prestigious award](https://www.natroxwoundcare.com/patrick-barron-vp-operations-wins-a-prestigious-award/) - Patrick Barron, Inotec AMD VP of Operations, has been recognised as one of the Top 100 most inspirational individuals working in UK industry by the The Manufacturer magazine. - [Inotec AMD Announces Enrolment Complete for NATROX® O₂ Trial](https://www.natroxwoundcare.com/inotec-amd-limited-announces-enrolment-completed-for-natrox-trial/) - Cambridge, UK – 18th February 2020 - Cambridge based Inotec AMD Limited is pleased to announce the conclusion of the enrolment phase of their USA Randomised Control Trial (RCT). - [MedTech Business Inotec AMD secures £7 VC Injection](https://www.natroxwoundcare.com/medtech-business-inotec-amd-secures-7-vc-injection/) - Inotec AMD has secured £7m in a funding round led by Praetura Ventures. - [Inotec Receives Federal Supply Schedule (FSS) award](https://www.natroxwoundcare.com/inotec-receives-federal-supply-schedule-fss-award/) - Inotec Receives Federal Supply Schedule (FSS) award - [National Institute for Health and Care Excellence (NICE) briefing on NATROX®](https://www.natroxwoundcare.com/national-institute-for-health-and-care-excellence-nice-briefing-on-natrox/) - The National Institute for Health and Care Excellence (NICE) have published a Medtech Innovation Briefing (MIB) document on NATROX® Oxygen Wound Therapy - [Dr. Harikrishna KR Nair initiates a NATROX® O₂ Clinical Trial in Malaysia](https://www.natroxwoundcare.com/dr-harikrishna-kr-nair-initiates-a-natrox-clinical-trial-in-malaysia/) - Dr. Harikrishna has initiated a 30-patient clinical trial in Malaysia to examine the effectiveness of NATROX® Oxygen Wound Therapy on non-healing diabetic foot ulcers. - [NATROX® O₂ Featured at International Scientific Conference](https://www.natroxwoundcare.com/natrox-features-at-an-international-scientific-conference/) - NATROX® Oxygen Wound Therapy was featured in one of the virtual scientific sessions during the International conference “The Science of Healing Advanced Wound Care” organised by Wounds UK. - [Karolina Gray Joins NATROX® Wound Care as Manufacturing Manager](https://www.natroxwoundcare.com/karolina-gray-joins-natrox-wound-care-as-manufacturing-manager/) - We're pleased to announce the addition of Karolina Gray to our team! She is joining as our new Manufacturing Manager and brings 11+ years of experience in manufacturing within the pharmaceutical industry. Our COO, John Adam, said, “We’re proud to have Karolina on our team. Our company is scaling up quickly, and manufacturing demands will only continue to increase. It’s important for us to cultivate an agile team capable of growing with us. Karolina has a proven track record with strong potential to continue her upward trajectory as a well-respected manager.” - [Dmitry Isaev Appointed New Product Development Manager](https://www.natroxwoundcare.com/dmitry-isaev-appointed-new-product-development-manager/) - Dmitry Isaev has joined as New Product Development Manager. Having worked as a NPD Engineer for Summit Medical, a company that develops products for orthopaedics, Dmitry gained R&D experience as a team leader developing concepts into prototypes and later into commercial products. Prior to this, he worked as a Design Quality Engineer for Intersurgical where - [NATROX® Oxygen Wound Therapy now listed on WoundSource](https://www.natroxwoundcare.com/natrox-oxygen-wound-therapy-now-listed-on-woundsource/) - Inotec AMD Inc is pleased to announce that NATROX® Oxygen Wound Therapy is now listed on WoundSource. ## Pages - [Home](https://www.natroxwoundcare.com/) - NATROX® O₂ is designed to heal chronic, hard-to-heal wounds. The innovative, simple device delivers continuous topical oxygen therapy 24-7 directly to wounds. - [About Us](https://www.natroxwoundcare.com/about-us/) - NATROX® Wound Care was founded to promote faster healing for chronic wound care patients. - [Reimbursement ](https://www.natroxwoundcare.com/reimbursement/) - If you treat DFUs, your input matters: review the proposed TOT coverage, draft comments, and join the August meeting. - [Wound Care Resource for Veterans](https://www.natroxwoundcare.com/wound-care-resources-for-veterans/) - Wound Care Resourcefor Veterans Help Veterans with non-healing wounds by knowing where to turn. Help connect Veterans with resources for non-healing wounds.If you work with Veterans through a VA facility, Veteran Service Organization, community organization, or outreach program, this resource can help you reach Veterans who may need additional wound care support. NATROX® O₂ is - [Patient FAQs](https://www.natroxwoundcare.com/patients/faqs/) - NATROX® O₂ Patient Help Center. Tips, tricks, and answers to frequently asked questions. Designed to empower patients. - [Clinician FAQs](https://www.natroxwoundcare.com/clinicians/faqs/) - Have questions about NATROX® O₂ continuous topical oxygen therapy? Explore frequently asked questions for clinicians. - [Improving Veterans' Quality of Life](https://www.natroxwoundcare.com/improving-quality-of-life-lp/) - Helping More VeteransHeal Chronic Wounds Trusted by Clinicians in 25+ VAMCs View evidence from: Sierra Nevada VA Salem VA Patients with a chronic wound have a 71% greater chance of healing using NATROX® O₂ than with standard of care alone.1 NATROX® O₂ Continuous Topical Oxygen Therapy delivers oxygen directly to a wound to aid in healing. - [Patients](https://www.natroxwoundcare.com/patients/) - NATROX® O₂ is a wearable Continuous Topical Oxygen Therapy (cTOT) device clinically proven to heal chronic wounds including diabetic foot ulcers, venous leg ulcers, and pressure injuries — worn 24/7 at home. - [Thank You | Improving Veterans' Quality of Life](https://www.natroxwoundcare.com/submission-successful/) - Reduction of Opioid Reliance VA PAVE Initiative Spinal Cord Injury Resource - [Reducing Amputation Risk in the U.S. Veteran Population](https://www.natroxwoundcare.com/reducing-amputation-risk-in-the-u-s-veteran-population/) - Key Points 80% of nontraumatic amputations in the VA start with diabetic foot ulcers (DFUs) Hypoxia is a primary barrier to healing in high-risk DFUs Most DFUs involve comorbidities that limit oxygen delivery Continuous topical oxygen therapy (cTOT) delivers oxygen directly to the wound site NATROX® O₂ supports tissue repair, angiogenesis, and infection control NATROX - [Clinicians](https://www.natroxwoundcare.com/clinicians/) - Explore how NATROX® O₂, a portable, non-invasive oxygen therapy device that promotes faster, sustained wound healing is making a difference. - [Evidence Pyramid Social Video](https://www.natroxwoundcare.com/evidence-pyramid-social-video/) - VIEW VIDEO References Theodorakopoulos G, Armstrong D. (2026) Topical Oxygen Therapy for Diabetic Foot Ulcers: Updated Evidence From Randomised Trials. Wound Repair Regen, 34:e70170. Link OuYang H, Yang J, Wan H, et al. (2024) Effects of different treatment measures on the efficacy of diabetic foot ulcers: a network meta-analysis. Front. Endocrinol, 15:1452192. Link Putri IL, - [Reimbursement Submission Successful](https://www.natroxwoundcare.com/reimbursement-submission-successful/) - Thank you for reaching out! We appreciate your interest in NATROX® O₂ Our team will review your request and reach out to you shortly with more details about reimbursement /coverage options. Learn more about the benefits of Continuous Topical Oxygen Therapy (cTOT) with NATROX® O2 Discover the Healing Power of NATROX® O2 Designed for wounds - [Booth Visitors Form](https://www.natroxwoundcare.com/booth-visitors-form/) - Fill out form. - [Portal](https://www.natroxwoundcare.com/portal/) - [Treating the Warfighter](https://www.natroxwoundcare.com/treating-the-warfighter/) - Key Points Severe injuries in theater and early post-evacuation often present with compromised perfusion, hypoxia, and high risk of infection. Without early intervention, necrosis progresses, wounds stall, and amputation risk increases. In trauma wounds, oxygen is often the missing element. Continuous topical oxygen therapy (cTOT) delivers oxygen directly to the wound site. NATROX® O₂ supports - [NATROX® O₂](https://www.natroxwoundcare.com/natrox-o2/) - Explore how NATROX® O₂, a portable, non-invasive oxygen therapy device that promotes fast, sustained wound healing is making a difference. Learn more. - [Strategic Alignment with Veterans Affairs](https://www.natroxwoundcare.com/natrox-o₂-effect-on-pain/) - Key Points Patients suffering from chronic wounds and associated pain are often negatively impacted by declining mental health and a reliance on opioids, which can contribute to increased suicide risks. Topics Covered Alignment between the VA and NATROX® O₂ missions to improve quality of life and reduce the use of opioids for pain. Evidence supporting - [Tradeshow Files](https://www.natroxwoundcare.com/portal/tradeshow-files/) - [Veteran Wound Healing LP](https://www.natroxwoundcare.com/veteran-wound-healing-lp/) - WATCH JAMES'S STORY How NATROX® O₂ Works NATROX® O₂ Continuous Topical Oxygen Therapy delivers oxygen directly to a wound to aid in healing. Patients with a chronic wound have a 71% greater chance of healing using NATROX® O₂ than with standard of care alone.1 I'd like more information... We will never share your info. Data Policy - [Presentation Gallery](https://www.natroxwoundcare.com/portal/presentation-gallery/) - Summary of evidence for NATROX® O₂ continuous topical oxygen therapy ranging from meta-analyses, RCTs, case series, expert recommendations, and pre-clinical work. - [Evidence Summary](https://www.natroxwoundcare.com/portal/evidence-summary/) - Summary of evidence for NATROX® O₂ continuous topical oxygen therapy ranging from meta-analyses, RCTs, case series, expert recommendations, and pre-clinical work. - [NATROX O₂ for Chronic, Non-Healing Wounds](https://www.natroxwoundcare.com/natrox-o₂-for-chronic-non-healing-wounds/) - Key Points Problem: Chronic, non-healing wounds due to insufficient wound perfusion. Solution: Topical Oxygen Therapy (cTOT) Method: ContinuousTopical Oxygen Therapy (cTOT) with NATROX® O₂ Topics Covered Indicated wound types When to consider NATROX® O₂ How NATROX® O₂ provides patient-centric care and wound care efficiency How to apply What to expect Supporting evidence View/Download Global Audience - [Home](https://www.natroxwoundcare.com/home/) - We deliver advanced solutions to aid wound healing. Our NATROX O2 continuous topical oxygen therapy is designed to heal chronic, non-healing wounds. - [Wound Care 101 Training](https://www.natroxwoundcare.com/wound-care-101/) - Wound Care 101 Training This Wound Care Education Series, presented by Windy Cole, DPM, will guide you through the wound healing process, treating various wound types and adopting algorithms for optimal patient outcomes. Below you will find a list of wound care course modules. The educational path requires you to take the courses in order - [NATROX® Reimbursement Landing Page](https://www.natroxwoundcare.com/natrox-reimbursement-lp/) - For Patients Non-VA Clinicians VA Clinicians Discover the Healing Power of NATROX® O2 Designed for wounds that aren't responding to standard of care, hear how NATROX® O2 has improved patient outcomes and quality of life. “I would highly recommend the NATROX® O2. The treatment saved my life.” – Bonnie, Patient "This magical little device (NATROX® - [Infocard](https://www.natroxwoundcare.com/infocard/) - [NATROX® O₂ Instructions For Use (IFU)](https://www.natroxwoundcare.com/home-2/natrox-o₂-instructions-for-use/) - NATROX® O₂ Instructions For Use (IFU) North Europe Issued: July 2024 Languages: English Swedish Finnish Norwegian Dutch Danish Modern Hebrew Estonian South Europe 1 Issued: March 2023 Languages: English French German Italian Spanish (Spain) Portuguese Arabic South Europe 2 Issued: March 2023 Languages English Croatian Greek Turkish Maltese Czech Slovenian Slovak Polish Bulgarian - [Branding](https://www.natroxwoundcare.com/portal/branding/) - [Request Information](https://www.natroxwoundcare.com/request-info/) - Interested in learning more about NATROX® O₂? Let's connect. - [Brochures](https://www.natroxwoundcare.com/portal/brochures/) - [HBOT](https://www.natroxwoundcare.com/portal/hbot/) - DFU cTOT/HBOT Wound Management Algorithm - [Logos](https://www.natroxwoundcare.com/portal/logos/) - [Icons](https://www.natroxwoundcare.com/portal/icons/) - [Patterns](https://www.natroxwoundcare.com/portal/patterns/) - [Continuous Topical Oxygen Therapy (cTOT) and Surgical Wound Dehiscence (SWD)](https://www.natroxwoundcare.com/continuous-topical-oxygen-therapy-ctot-and-surgical-wound-dehiscence-swd/) - Rapidly treat surgical wound dehiscence with NATROX® O₂. Discover how cTOT supports healing and prevents complications in real cases. - [NATROX® Wound Solutions](https://www.natroxwoundcare.com/natrox-wound-solutions/) - Why NATROX® Wound Solutions? There is a need for consistency across wound care that will move the focus from wound management to patient healing. But today’s marketplace is saturated with multiple products and therapies that offer minimal innovation and result in confusion for the clinician. Consequently, the treatments are often used in isolation rather than - [Contact](https://www.natroxwoundcare.com/contact/) - Have questions or want more information about NATROX® O₂ topical wound care therapy product? Let's connect. - [Application Videos](https://www.natroxwoundcare.com/application-videos/) - Step-by-step tips to apply NATROX® O₂ continuous topical oxygen therapy. Valuable best practices to improve the healing process for non-healing chronic wounds. - [Community Care at the VA](https://www.natroxwoundcare.com/portal/community-care-at-the-va/) - [Careers](https://www.natroxwoundcare.com/careers/) - A career with NATROX® means you can make an impact. We were founded to promote faster healing for chronic wound care patients across the world. Explore now. - [Wound Care 101 Training](https://www.natroxwoundcare.com/portal/wound-care-101-training/) - Wound Care 101 Training This Wound Care Education Series, presented by Windy Cole, DPM, will guide you through the wound healing process, treating various wound types and adopting algorithms for optimal patient outcomes. Below you will find a list of wound care course modules. The educational path requires you to take the courses in order - [NY25 Workshop](https://www.natroxwoundcare.com/ny25-workshop/) - Breathing Life into Non-Healing Wounds: Continuous Topical Oxygen Therapy as an Adjunct to Standard of Care Unlock the potential of leading-edge wound care with NATROX® O₂, a revolutionary wearable device delivering Continuous Topical Oxygen Therapy (cTOT). Join us for an engaging session where med tech meets simplicity, and discover how this breakthrough solution is transforming healing - [New York Reimbursement for NATROX® O₂](https://www.natroxwoundcare.com/nylp/) - Uses the natural properties of oxygen to heal Patients with a chronic wound have a 71% greater chance of healing using NATROX® O2 topical oxygen therapy than with standard of care alone.1 Sally's Pain-Free Miracle: A NATROX® O₂ Testimonial at 91 - [Newsletter](https://www.natroxwoundcare.com/newsletter/) - Get the latest insights, clinical updates, and product innovations in wound care. Subscribe to the NATROX® Wound Care newsletter today! - [Evidence](https://www.natroxwoundcare.com/evidence/) - [Case Studies](https://www.natroxwoundcare.com/portal/case-studies-portal/) - Case Studies In-depth review of patient cases in their real-life contexts Browse Case Studies View all case study details on our corporate website. See the cover image, read an overview, and see a snapshot of key details. NOTE: This page will open in a new browser. Browse Case Studies on our Website - [FAQ Discussion Guide](https://www.natroxwoundcare.com/portal/faq-discussion-guide/) - [Thank you](https://www.natroxwoundcare.com/request-info/thank-you/) - [Journal Articles](https://www.natroxwoundcare.com/portal/journal-articles-portal/) - Browse Journal Articles Access all journal articles on our corporate website. See the cover image, read an overview, and see a snapshot of key details. NOTE: This page will open in a new browser. Browse Journal Articles on our Website - [Posters](https://www.natroxwoundcare.com/portal/posters-portal/) - Browse Posters Access all posters on our corporate website. See the cover image, read an overview, and see a snapshot of key details. NOTE: This page will open in a new browser. Browse Posters on our Website - [Desert Foot 2024 Posters](https://www.natroxwoundcare.com/sawc-fall-2024-posters/) - Desert Foot 2024 Posters The Use of Continuous Topical Oxygen Therapy (cTOT) in Combination with Cellular, Acellular and Matrix-like Products to Treat Complex, Chronic Wounds: a Retrospective Case Series Dr. Naz Wahab, MD; Lisa Thomas, RN; Dr. Windy Cole, DPM, CWSP VIEW HERE Continuous Topical Oxygen Therapy as Part of the Reconstructive Ladder of Limb - [SAWC Fall 2024](https://www.natroxwoundcare.com/sawc-fall-2024/) - [NATROX O₂ for SCI Veterans](https://www.natroxwoundcare.com/natrox-o₂-for-sci-veterans/) - Key Information Explains how the physiological changes in patients with spinal cord injuries (SCI) affect wound healing. Presents evidence showing how continuous topical oxygen therapy (cTOT) with NATROX® O₂ may help. Provides instructions on how to order. References Rappl LM. (2008) Physiological changes in tissues denervated by spinal cord injury tissues and possible effects on - [Troubleshooting](https://www.natroxwoundcare.com/portal/troubleshooting/) - [Educational Material](https://www.natroxwoundcare.com/portal/educational-material/) - [Complaint Form](https://www.natroxwoundcare.com/portal/complaint-form/) - [Advertising](https://www.natroxwoundcare.com/portal/advertising/) - [SAWC Spring 2024 Posters](https://www.natroxwoundcare.com/sawc-spring-2024-posters/) - SAWC Spring 2024 Posters Impact of Continuous Topical Oxygen Therapy (cTOT) on Biofilm Gene Expression in a Porcine Tissue Model Christopher Bell, PhD; Hannah Jones; Hannah Thomas; Dr. Emma Woodmansey PhD; Gregory Schultz, PhD Download The Role of Continuous Topical Oxygen Therapy (cTOT) as an Adjunctive Treatment in Non-Healing Chronic Wounds; a South African Perspective - [Videos](https://www.natroxwoundcare.com/portal/videos-portal/) - Videos Browse Application Videos View our page dedicated to the easy application of NATROX® O₂. Easy to watch videos and share with clinical contacts. NOTE: This page will open in a new browser. Browse Application Videos on our Website Browse Videos View all videos on our corporate website. See the cover image, read an overview - [Videos - Archive](https://www.natroxwoundcare.com/portal/videos/) - [Posters - Archive](https://www.natroxwoundcare.com/portal/posters/) - [Journal Articles - Archive](https://www.natroxwoundcare.com/portal/journal-articles/) - [Case Studies - Archive](https://www.natroxwoundcare.com/portal/case-studies/) - [References](https://www.natroxwoundcare.com/portal/references/) - [Sales](https://www.natroxwoundcare.com/portal/sales-navigation/) - [Evidence](https://www.natroxwoundcare.com/portal/evidence-navigation/) - [Marketing](https://www.natroxwoundcare.com/portal/marketing-navigation/) - [Test](https://www.natroxwoundcare.com/test/) - [Product Images](https://www.natroxwoundcare.com/portal/product-images/) - [Login](https://www.natroxwoundcare.com/login/) - [Thank You | NYLP](https://www.natroxwoundcare.com/nylp-thankyou/) - [Webinar Training](https://www.natroxwoundcare.com/portal/webinar-training/) - [Evaluation](https://www.natroxwoundcare.com/portal/evaluation/) - [Digital Campaigns](https://www.natroxwoundcare.com/portal/digital-campaigns/) - [Online Bookcase](https://www.natroxwoundcare.com/portal/online-bookcase/) - [Privacy](https://www.natroxwoundcare.com/privacy/) - Privacy Policy This Privacy Policy governs the manner in which we collect, use, maintain and disclose information collected from users of this site. Personal identification information We may collect personal identification information from users in a variety of ways, including, but not limited to, when users visit our site, fill out a form, and in ## Resources - [A multicenter clinical trial evaluating the durability of diabetic foot ulcer healing in ulcers treated with topical oxygen and standard of care versus standard of care alone 1 year post healing](https://www.natroxwoundcare.com/resource/a-multicenter-clinical-trial-evaluating-the-durability-of-diabetic-foot-ulcer-healing-in-ulcers-treated-with-topical-oxygen-and-standard-of-care-versus-standard-of-care-alone-1-year-post-healing/) - Multicenter clinical trial evaluating durability of DFU healing 1-year post-healing for ulcers treated with topical oxygen plus SoC versus SoC alone. - [Podcast: Pain and the Journey of the Chronic Wound Patient](https://www.natroxwoundcare.com/resource/podcast-pain-and-the-journey-of-the-chronic-wound-patient/) - 🎙️ New Podcast Alert! Join us as we explore the profound impact of topical oxygen therapy on chronic wound patients' pain journey. Windy Cole, DPM, CWSP, FACCWS, speaks with the Podiatry Today editorial staff and shares insights on how topical oxygen therapy has significantly decreased patient wound pain in her practice. 🎧 Listen to the - [Managing Chronic Wound Pain with Topical Oxygen Therapy: Insights from Dr. Windy Cole](https://www.natroxwoundcare.com/resource/managing-chronic-wound-pain-with-topical-oxygen-therapy-insights-from-dr-windy-cole/) - Explore chronic wound pain management with Dr. Windy Cole. Hear her insights on topical oxygen therapy's transformative potential in enhancing patient outcomes. - [Breathing Life Into Wounds](https://www.natroxwoundcare.com/resource/breathing-life-into-wounds/) - This study aims to evaluate the efficacy of topical oxygen therapy in managing hard to heal chronic wounds. - [How NATROX® O₂ Saved My Leg: A Testimonial of Hope and Healing](https://www.natroxwoundcare.com/resource/how-natrox-o₂-saved-my-leg-a-testimonial-of-hope-and-healing/) - In this powerful testimonial, Karen from Manchester, UK shares her emotional journey from facing the possibility of leg amputation to discovering the life-changing benefits of NATROX® O₂. After developing a serious infection from what seemed like a minor injury, Karen's health deteriorated, and she was told her only option was an above-the-knee amputation. However, after - [Use of Continuous Topical Oxygen Therapy in Combination to Optimize the Chronic Wound Environment Prior to Cellular, Acellular, and Matrix-Like Product Application: A Retrospective Case Series](https://www.natroxwoundcare.com/resource/the-use-of-continuous-topical-oxygen-therapy-in-combination-with-cellular-acellular-and-matrix-like-products-to-treat-complex-chronic-wounds-a-retrospective-case-series-2/) - Discover how the NATROX O2 randomized clinical trial addresses critical issues in DFU trial design. Gain insights for future advancements. - [American Diabetes Association (ADA) Standards of Care in Diabetes 2026](https://www.natroxwoundcare.com/resource/american-diabetes-association-ada-standards-of-care-in-diabetes/) - Topical Oxygen Therapy (TOT) was awarded an A-grade for evidence by the ADA and recommended as an adjunctive treatment recommendation for diabetic foot ulcers. - [A Veteran's Triumph Over Non-Healing Wounds with NATROX® O₂](https://www.natroxwoundcare.com/resource/a-veterans-triumph-over-non-healing-wounds/) - Meet James Sass, a 79-year-old U.S. Army Veteran and Cherokee Nation citizen, who faced life-altering chronic wounds caused by peripheral neuropathy—a condition he developed after exposure to Agent Orange during his service in Vietnam. James battled painful, non-healing leg ulcers that delayed his hip surgery, ultimately leaving him immobile and dependent on a wheelchair for - [A Complex Surgical Wound Dehiscence Case Managed with Continuous Topical Oxygen Therapy](https://www.natroxwoundcare.com/resource/a-complex-surgical-wound-dehiscence-case-managed-with-continuous-topical-oxygen-therapy/) - Chronic limb threatening ischaemia (CLTI) is associated with mortality, limb amputation and impaired quality of life. - [Continuous Topical Oxygen Therapy Used in a Nursing Home Setting to Promote Closure of a Non-Healing Pressure Ulcer: A Case Study](https://www.natroxwoundcare.com/resource/continuous-topical-oxygen-therapy-used-in-a-nursing-home-setting-to-promote-closure-of-a-non-healing-pressure-ulcer-a-case-study/) - Case study to observe effect of (cTOT) as an adjunctive treatment to (SoC) on a non-healing, category 3 pressure ulcer in a PLWD and lower limb lymphoedema. - [Case Study Examining the Efficacy of Continuous Topical Oxygen Therapy in Managing Chronic Ischemic Wounds Associated with Buerger’s Disease](https://www.natroxwoundcare.com/resource/efficacy-of-ctot-managing-chronic-ischemic-wounds-associated-with-buergers-disease/) - Learn how continuous topical oxygen therapy (cTOT) supports healing in ischemic foot ulcers and Buerger’s disease. Evidence-based limb salvage solution for U.S. wound care clinicians. - [Healing Journeys Unveiled: Clinicians, Patients, and Caregivers Share the Power of NATROX® O₂](https://www.natroxwoundcare.com/resource/healing-journeys-unveiled-clinicians-patients-and-caregivers-share-the-power-of-natrox-o₂/) - Step into the world of wound care through the eyes of those who lived it. In this extraordinary testimonial, Dr. Wahab, a dedicated wound care specialist, together with patients and their caregivers, unfolds their remarkable journey to healing with NATROX® O₂. From the struggles of chronic, non-healing wounds to the transformative impact of continuous topical - [Topical Oxygen Therapy in the Management of Hard-to-Heal Wounds in Colombia: A Retrospective Review](https://www.natroxwoundcare.com/resource/topical-oxygen-therapy-in-the-management-of-hard-to-heal-wounds-in-colombia-a-retrospective-review/) - Chronic limb threatening ischaemia (CLTI) is associated with mortality, limb amputation and impaired quality of life. - [Shared Decision-Making in Wound Management](https://www.natroxwoundcare.com/resource/shared-decision-making-in-wound-management/) - Dr. Windy Cole explains how shared decision-making (SDM) in wound management empowers patients and how NATROX® O₂ supports this. - [Antimicrobial Resistance in Wound Care](https://www.natroxwoundcare.com/resource/antimicrobial-resistance-in-wound-care/) - Expert panel consensus statement: Antimicrobial Resistance in Wound Care led by Dr. Windy Cole, Global Medical Affairs Director for NATROX® Wound Care. - [Why Robust Wound Healing Matters for Prosthetic Users: The Role of Continuous Topical Oxygen Therapy](https://www.natroxwoundcare.com/resource/why-robust-wound-healing-matters-for-prosthetic-users-the-role-of-continuous-topical-oxygen-therapy/) - Author: Windy Cole, DPM For patients with limb loss, wound closure is only the first step toward recovery. As highlighted in this case study, reintroducing a prosthetic limb can be a painful and risky process if the newly healed skin is fragile. That’s why robust healing is essential. NATROX® O₂ delivers Continuous Topical Oxygen Therapy - [After 5 Years of Struggle, NATROX® O₂ Healed Her Mom’s Wound](https://www.natroxwoundcare.com/resource/after-5-years-of-struggle-natrox-o₂-healed-her-moms-wound/) - A Daughter’s Story: How Topical Oxygen Therapy Helped Heal a 5-Year Chronic Wound “My mother suffered from a chronic wound for nearly five years. We tried everything—government hospitals, endless antibiotics, supplements, and daily dressings. Nothing worked.”– Umma, daughter and caregiver In this powerful patient testimonial, Umma shares the emotional journey of her mother’s non-healing wound - [Healing a Chronic Venous Leg Ulcer with NATROX® O₂](https://www.natroxwoundcare.com/resource/healing-a-chronic-venous-leg-ulcer-with-natrox-o₂/) - Discover how NATROX® O₂ helped transform the life of a patient suffering from a chronic venous leg ulcer that had not healed for 9 months. 🔍 Diagnosis: Venous leg ulcer (re.UE lateral) Persistent, non-healing wound despite multiple interventions 🚫 Before NATROX® O₂: Multiple failed treatments across institutions Poor patient compliance due to pain Refusal of - [When Conventional Treatment Fails: A Wearable Continuous Topical Oxygen Therapy System Reduces Wound Volume in Chronic Venous Leg Ulcers](https://www.natroxwoundcare.com/resource/when-conventional-treatment-failsa-wearable-continuous-topical-oxygen-therapy-system-reduces-wound-volume-in-chronic-venous-leg-ulcers/) - Authors: Patricia Manavbasi, BSN, RN, CWON, CFCN; Lisa Foster, MSN, RN, PHN, CWON, CFCN, CFCS The findings in the poster highlight cTOT as an essential complement to standard of care for non-healing VLUs. Click to Download Location: U.S. Department of Veteran Affairs Veterans Health Administration Sierra Nevada Healthcare System Overview: This poster highlights that many - [Exploring the Efficacy of Continuous Topical Oxygen Therapy for Diverse Chronic Wound Types: Real-World Case Studies](https://www.natroxwoundcare.com/resource/exploring-the-efficacy-of-continuous-topical-oxygen-therapy-for-diverse-chronic-wound-types-real-world-case-studies/) - CLICK TO VIEW POSTER Overview The poster presents a selection of international case studies involving NATROX® O₂ on wounds such as burns, surgical wound dehiscence (SWD), and calciphylaxis. Results Case 1 (United States) - SWD following radical fasciotomy showing complete closure in 77 days. Case 2 (South Africa) - Full-thickness burns on the thigh, achieving - [Breaking Barriers in Peripheral Artery Disease (PAD) and Diabetic Foot Ulcer (DFU) Care](https://www.natroxwoundcare.com/resource/breaking-barriers-in-peripheral-artery-disease-pad-and-diabetic-foot-ulcer-dfu-care/) - Explore how cTOT & telehealth improve healing in Peripheral Artery Disease (PAD)-related diabetic foot ulcers, reducing barriers to care and improving outcomes. - [How NATROX® O₂ Supports Antimicrobial Stewardship](https://www.natroxwoundcare.com/resource/how-natrox-o₂-supports-antimicrobial-stewardship/) - Learn how NATROX® O₂ supports antimicrobial stewardship in wound care by enhancing antimicrobial effectiveness and tackling biofilm-related infections. - [International Consensus Document - Cellular, Acellular and Matrix-Like Products (CAMPs) in Pressure Injuries](https://www.natroxwoundcare.com/resource/international-consensus-document-cellular-acellular-and-matrix-like-products-camps-in-pressure-injuries/) - CLICK TO VIEW ARTICLE Overview This consensus document explores the issue and prevalence of pressure injuries, emphasizing the essential role of CAMPs and other emerging treatment strategies in their management. Among these approaches, topical oxygen therapy is highlighted as a key consideration in promoting wound healing. Main Points in this Publication that relate to NATROX® - [Continuous Topical Oxygen Therapy (cTOT) Used to Support Healing of a Recalcitrant Donor Site Wound](https://www.natroxwoundcare.com/resource/continuous-topical-oxygen-therapy-ctot-used-to-support-healing-of-a-recalcitrant-donor-site-wound/) - 5-year duration recalcitrant donor site wound in patient with LcSSc: a case report - [How Three Patients Found Hope, Healing, and a Second Chance Through the “Living Without Wounds” Program by CureLATAM](https://www.natroxwoundcare.com/resource/how-three-patients-found-hope-healing-and-a-second-chance-through-the-living-without-wounds-program-by-curelatam/) - What if a wound that refused to heal for months—or even years—could finally close? For many patients living with diabetes, hypertension, venous disease, or traumatic injuries, chronic wounds become more than a medical condition; they become a daily burden, a source of fear, and a threat to independence. But for Beatriz, Elvia, and Fanny, hope - [Mechanistic Insights and International Use Cases of cTOT in Wound Management](https://www.natroxwoundcare.com/resource/mechanistic-insights-and-international-use-cases-of-ctot-in-wound-management/) - Expert panel consensus statement: Antimicrobial Resistance in Wound Care led by Dr. Windy Cole, Global Medical Affairs Director for NATROX® Wound Care. - [The Power of Oxygen in Wound Healing — and How NATROX® O₂ Helps Restore It ](https://www.natroxwoundcare.com/resource/the-power-of-oxygen-in-wound-healing-and-how-natrox-o₂-helps-restore-it/) - EVERY STAGE OF WOUND HEALING DEPENDS ON OXYGEN From injury to the final stages of tissue remodeling, oxygen fuels the cellular activity that allows wounds to repair, close, and strengthen. But in many chronic wounds, oxygen levels are severely reduced — resulting in stalled wound healing. Let’s explore how oxygen drives each stage of healing, and how new delivery - [Chronic Wound Treatment](https://www.natroxwoundcare.com/resource/chronic-wound-treatment/) - Explore how holistic approaches and innovative technologies like NATROX® O₂ revolutionize chronic wound treatment, addressing all aspects of patient well-being. - [Diabetic Foot Ulcer Treatment](https://www.natroxwoundcare.com/resource/diabetic-foot-ulcer-treatment/) - Chronic diabetic foot ulcers (DFUs) remain a significant clinical challenge, especially when standard of care falls short. In a compelling lecture at EWMA 2025, Prof. Dr. José Luis Lázaro Martínez delivered a focused message: there is no bad therapy, only bad indications. His discussion centered on the importance of appropriate patient selection and timely intervention - [Unlocking Wound Healing Potential: Insights on NATROX® O₂ Therapy with Dr. Windy Cole, DPM, CWSP](https://www.natroxwoundcare.com/resource/unlocking-wound-healing-potential-dr-cole-topical-oxygen/) - Dr. Windy Cole discusses the role of NATROX® O₂ topical oxygen therapy in chronic wound healing at the SAWC Fall 2023 Innovation Spotlight. - [Topical Oxygen Therapy Meta-Analyses](https://www.natroxwoundcare.com/resource/topical-oxygen-therapy-meta-analyses/) - With six meta-analyses on Topical Oxygen Therapy for chronic wounds including 13 RCTs and more than 1,000 patients, evidence indicates TOT is effective and safe for various wound types. - [Using cTOT and leveraging a digital platform changes how and where we deliver wound care while optimizing both clinical outcomes and limited resources](https://www.natroxwoundcare.com/resource/drlee_poster_dfcon2022/) - Author: Dr. Aliza Lee, DPM, MS, ABPMPresented at: DFCon 2022Keywords: cTOT, telehealth, home care, remote monitoring Clinical poster by Dr. Aliza Lee, DPM, MS, ABPM, Director of Podiatric Medical Education, Staff Podiatrist & Clinical Research Investigator at the V.A. Hospital in Salem, Virginia. 12-week study on 8 patients exploring the combined use of NATROX® O₂ with an advanced - [M.O.I.S.T. Concept for the Local Therapy of Chronic Wounds: An International Update](https://www.natroxwoundcare.com/resource/moist-concept-for-local-therapy-of-chronic-wounds-international-update/) - New insights on wound pain management and holistic care. Explore international perspectives on assessments, challenges and treatment options for chronic wounds. - [The Use of Topical Oxygen Therapy in Complex Surgical Wounds](https://www.natroxwoundcare.com/resource/the-use-of-topical-oxygen-therapy-in-complex-surgical-wounds/) - Explore the transformative impact of topical oxygen therapy on complex surgical wounds through a clinical evaluation. Discover how this innovative therapy promotes wound healing and enhances patients' quality of life. Download the comprehensive PDF for detailed case studies and expert analysis. - [Continuous Topical Oxygen Therapy – Improving Healing in the Diabetic Foot](https://www.natroxwoundcare.com/resource/drlee_poster_dfcon2021/) - Author: Dr. Aliza Lee, DPM, MS, ABPMPresented at: DFCon 2021Keywords: DFUs, VA, USA, home care Clinical poster by Dr. Aliza Lee, DPM, MS, ABPM, Director of Podiatric Medical Education, Staff Podiatrist & Clinical Research Investigator at the V.A. Hospital in Salem, Virginia. Case study results on 5 patients with complex or non-healing diabetic foot ulcers not responding to - [TOT in the Treatment of DFUs: Randomised controlled clinical trial (RCT)](https://www.natroxwoundcare.com/resource/145-patient-study-demonstrates-significantly-increased-healing-with-natrox-o2-rct-usrct/) - Topical oxygen therapy in the treatment of diabetic foot ulcers: a multicentre, open, randomised controlled clinical trial Journal of Wound Care, May 2021 Author: Thomas E Serena, Neal M Bullock, Windy Cole, John Lantis, Lam Li, Sarah Moore, Keyur Patel, Matthew Sabo, Naz Wahab, Patricia Price Keywords: chronic wound, clinical trial, diabetes, diabetic foot ulcer, DFU, dressing, - [Supplementary oxygen and wound healing](https://www.natroxwoundcare.com/resource/supplementary-oxygen-and-wound-healing/) - DOWNLOAD NOW Wounds International, 2019 Author: Sonia Silvestrini Citation: Silvestrini, S., 2019. Supplementary oxygen and wound healing. Wounds International, 10(4), 50-56. Keywords: Chronic/complex wounds, compliance, concordance, pain relief, patient lifestyle, wound assessment Key points: The author, Sonia Silvestrini, is a clinical nurse specialist in Rome who runs multiple clinics dealing with chronic wounds. Sonia has used NATROX® - [The role of cTOT as an adjunctive treatment in non-healing chronic wounds; A South African perspective](https://www.natroxwoundcare.com/resource/the-role-of-continuous-topical-oxygen-therapy-ctot-as-an-adjunctive-treatment-in-non-healing-chronic-wounds-a-south-african-perspective/) - Discover insights on continuous Topical Oxygen Therapy's role in wound care. Download the poster for valuable research findings. - [From Hole to Healing: Gloria's NATROX® O₂ Journey](https://www.natroxwoundcare.com/resource/from-hole-to-healing-glorias-natrox-o₂-journey/) - Discover the incredible healing journey of Gloria, a NATROX® O₂ patient, as she shares her experience with wound care after the removal of a tumor in December 2021. Join her as she recounts the shooting pain, the gradual disappearance, and the surprising effectiveness of NATROX® O₂ in closing the wound. Witness the transformative power of - [The role of topical oxygen therapy in the treatment of diabetic foot ulceration](https://www.natroxwoundcare.com/resource/the-role-of-topical-oxygen-therapy-in-the-treatment-of-diabetic-foot-ulceration/) - DOWNLOAD NOW Authors: Dr Nia. J. Jones, Gail Curran, Nicola. M. Ivins, Professor Keith. G. Harding, Mr Paul D. Hayes Introduction: Oxygen is a prerequisite in wound healing. It supports several pathophysiological processes such as cell proliferation, bacterial defence, angiogenesis and collagen synthesis. Even though the role of topical oxygen therapy in wound healing is - [NATROX® O₂ stimulates healing in difficult chronic wounds: a tertiary centre experience](https://www.natroxwoundcare.com/resource/natrox-oxygen-wound-therapy-stimulates-healing-in-difficult-chronic-wounds-a-tertiary-centre-experience/) - DOWNLOAD NOW Publication: Journal of Wound Care, 2018 Authors: Hanna Kaufman, Maxim Gurevich, Eran Tamir, Elad Keren, Lipkin Alexander, Paul Hayes Keywords: Chronic wound, home care, new technology, tertiary centre, topical oxygen, wound healing Key points: 100-patient case series study carried out in Israel – “real world setting.” Mixed aetiology wounds. Mean wound duration of 15 months. All - [International Consensus: Use of Topical Oxygen Therapy in Wound Healing - JoWC Sep 2023](https://www.natroxwoundcare.com/resource/international-consensus-document-use-of-topical-oxygen-therapy-in-wound-healing-jowc-sep-202/) - The panel endorses Topical Oxygen as an adjunct therapy to SoC for chronic wounds, recommending its use if a wound has not reduced by 50% after 4 weeks. - [Topical Oxygen Therapy in Hard-to-Heal Wounds in Cardiac Surgery](https://www.natroxwoundcare.com/resource/topical-oxygen-therapy-in-hard-to-heal-wounds-in-cardiac-surgery/) - Explore the latest poster on cTOT by Viviana Gonçalves. Discover how this innovative treatment enhances healing in hard-to-heal wounds in cardiac surgery. - [Accelerating Healing in a Chronic Venous Leg Ulcer with NATROX® O₂](https://www.natroxwoundcare.com/resource/non-healing-venous-leg-ulcer/) - This case study features a 76-year-old male with a 54-week venous leg ulcer (VLU) on the inner aspect of his right leg. His medical history included venous insufficiency, atrial fibrillation, psoriasis, and osteoporosis — all contributing factors that increased the risk of skin breakdown and ulcer recurrence. Despite 12 months of standard care, including compression - [Breaking the Biofilm Barrier: How NATROX® O₂ Helps Restore Healing in Chronic Wounds](https://www.natroxwoundcare.com/resource/challenging-wounds-improving-outcomes-biofilm-management-with-topical-oxygen-therapy/) - Learn how topical oxygen therapy with NATROX® O₂ helps disrupt biofilms, restore healing, and improve outcomes in chronic, hard-to-heal wounds. - [Consensus round table meeting: Portable topical oxygen therapy for healing complex wounds](https://www.natroxwoundcare.com/resource/consensus-round-table-meeting-portable-topical-oxygen-therapy-for-healing-complex-wounds/) - Chronic and complex wounds continue to challenge clinicians and health systems worldwide. Despite adherence to standard of care, many wounds fail to progress as expected, highlighting the need for advanced, evidence-based adjunct therapies. An expert round table consensus, led by clinical leaders in wound care, recognized the growing role of topical oxygen therapy (TOT) and - [Case Study: Non-healing venous leg ulcer (VLU)](https://www.natroxwoundcare.com/resource/non-healing-venous-leg-ulcer-2/) - Read how an 85-year-old patient with a chronic venous leg ulcer unresponsive to compression therapy achieved complete healing in 11 weeks using NATROX® Oxygen Wound Therapy. - [Case Study: Healing a Non-Healing Diabetic Foot Ulcer (DFU)](https://www.natroxwoundcare.com/resource/non-healing-diabetic-foot-ulcer/) - This case study by Windy Cole, DPM highlights the successful treatment of a 42-year-old patient with a 14-week history of a non-healing diabetic foot ulcer. Despite standard of care—including regular debridement, off-loading, and topical antimicrobials—the wound failed to progress. The patient also faced comorbidities such as COPD, hypertension, obesity, and diabetes-related anxiety and depression. Following - [Case Study: Non-healing leg trauma wound](https://www.natroxwoundcare.com/resource/non-healing-leg-trauma-wound-2/) - Author: Windy Cole, DPM HISTORYThis 85-year-old female presented with a traumatic injury to her right lower leg. This is a common wound seen in this patient population due to decreased elasticity and turgor found in aging skin. This patient has a significant past medical history including insulin dependent diabetes, chronic kidney disease, anaemia, coronary artery - [Barriers Eliminated: An Advanced Digital Wound Platform Combined with Continuous Topical Oxyen Therapy Improves Access, Saves Time, and Decreases Wound Size in Complex Diabetic Patients](https://www.natroxwoundcare.com/resource/barriers-eliminated-dr-lee-poster-sawc-spring-2023/) - Author: Dr. Aliza Lee, DPM, MS, ABPMPresented at: SAWC Spring 2023Keywords: DFUs, PAD, telehealth, cTOT, advanced digital platform Clinical poster by Dr. Aliza Lee, DPM, MS, ABPM, Director of Podiatric Medical Education, Staff Podiatrist & Clinical Research Investigator at the V.A. Hospital in Salem, Virginia. A 12-week study on 8 patients exploring the combined use of NATROX® O₂ - [Non-healing pressure injury](https://www.natroxwoundcare.com/resource/non-healing-pressure-injury/) - Keywords: best practices, stopping & starting Key points: Use NATROX® O₂ continually until the wound is fully healed. 12 months of open wound, healed in 12 weeks. Significant improvement initially with NATROX® O₂. NATROX® O₂ therapy stopped too early (after 6 weeks), and the wound deteriorated within 1 month. NATROX® O₂ re-started and the wound healed completely - [Continuous Topical Oxygen Therapy as Part of the Reconstructive Ladder of Limb Salvation: a Case Series](https://www.natroxwoundcare.com/resource/ctot-part-of-reconstructive-ladder-of-limb-salvation/) - Explore how continuous topical oxygen therapy supports healing in elderly patients with chronic radiation-induced wounds. Learn more about this groundbreaking approach. - [An Observational Clinical Trial Examining the Effect of Topical Oxygen Therapy (Natrox™) on the Rates of Healing of Chronic Diabetic Foot Ulcers](https://www.natroxwoundcare.com/resource/an-observational-clinical-trial-examining-the-effect-of-topical-oxygen-therapy-natrox-on-the-rates-of-healing-of-chronic-diabetic-foot-ulcers/) - VIEW PDF VIEW ON SAGE JOURNALS Abstract: NATROX topical oxygen therapy (TOT) (Inotec AMD Ltd, Hertfordshire, UK) employs a small battery-powered “oxygen generator” to concentrate atmospheric oxygen and feeds highly concentrated oxygen through a fine, soft tube to a dressinglike “oxygen distribution system”, which is placed over the wound and is held in place by - [The Use of Topical Oxygen Therapy to Treat a Calciphylaxis Wound During a Global Pandemic: A Case Report](https://www.natroxwoundcare.com/resource/the-use-of-topical-oxygen-therapy-to-treat-a-calciphylaxis-wound-during-a-global-pandemic-a-case-report/) - Citation: Cole W, Yoder CM, Coe S. The Use of Topical Oxygen Therapy to Treat a Calciphylaxis Wound During a Global Pandemic: A Case Report. Wounds. 2020 Nov;32(11):294-298. PMID: 33465045. Abstract Introduction: Calciphylaxis is a rare, highly morbid pathological syndrome of vascular calcification and tissue necrosis. It is predominantly seen in patients with end-stage renal disease - [Case series: the impact of NATROX® O₂ on patients with DFUs](https://www.natroxwoundcare.com/resource/case-series-the-impact-of-natrox-oxygen-wound-therapy-system-on-patients-with-diabetic-foot-ulcers/) - DOWNLOAD NOW Title: Case series: the impact of NATROX® Oxygen Wound Therapy System on patients with diabetic foot ulcers Diabetic Foot Journal, 2017 Authors: Gail Curran, Catherine Fisher, Paul Hayes, Ian Loftus, Leanne Sequeira Keywords: diabetic foot ulcer, HBOT comparison, home care, oxygen, wound therapy Key points: The cost of diabetes to the NHS. These numbers can - [NATROX® O₂ Case Reports: Evaluating the outcomes of 8 DFU patients](https://www.natroxwoundcare.com/resource/natrox-case-reports-evaluating-the-outcomes-of-eight-patients-with-dfus/) - DOWNLOAD NOW Title: Evaluating the outcomes of 8 patients with diabetic foot ulcers using a new topical oxygen delivery device Authors: Dr. Harikrishna KR Nair Citation: Nair, H.KR, 2019. Evaluating the outcomes of 8 patients with diabetic foot ulcers using a new topical oxygen delivery device, Wounds Asia, 2(1): 40-43. Keywords: Compliance, concordance, DFU, PAD Key points: - [NATROX® O₂ - Let the topical oxygen flow for healing complex wounds](https://www.natroxwoundcare.com/resource/natrox-let-the-topical-oxygen-flow-for-healing-complex-wounds/) - Authors: Edward C Choke, John CC Wang, Harikrishna KR Nair, Tze T Chong, Tjun Y Tang Publication: Wounds Asia, 2018 Citation: Choke EC, Nair HKR, Wang JCC, et al. (2018) NATROX® - Let the topical oxygen flow for healing complex wounds. Wounds Asia, 1(2):30-3. Keywords: Complex & chronic wounds, traumatic wounds, wound assessment Key points: Discuss the key - [Case series: Using NATROX® O₂ in management of DFUs](https://www.natroxwoundcare.com/resource/case-series-using-natrox-oxygen-wound-therapy-in-the-management-of-diabetic-foot-ulcers/) - This document contains a series of case reports describing the use of NATROX® O₂ topical oxygen therapy for wounds in patients with DFUs, alongside local protocol and guidelines. Title: Case series: Using NATROX® Oxygen Wound Therapy in the management of diabetic foot ulcers Wounds UK, 2019 Authors: Debbie Wilson, Kaye McIntyre, Paul Goodfellow, Diane Knowles, Elaine - [How wound care clinicians can optimize clinical outcomes and resources](https://www.natroxwoundcare.com/resource/how-wound-care-clinicians-can-optimize-clinical-outcomes-and-resources/) - Dr. Aliza Lee, DPM, MS, ABPM, Director of Podiatric Medical Education, Staff Podiatrist, and Clinical Research Investigator at the VA Medical Center in Salem, Virginia, presents her latest 12-week study on 8 patients exploring the combined use of NATROX® O₂ with an advanced digital platform using Telehealth to understand the clinical benefits. Results showed: • - [Case Series Examining the Efficacy of cTOT in Treatment of DFUs](https://www.natroxwoundcare.com/resource/case-series-examining-the-efficacy-of-continuous-topical-oxygen-therapy-in-the-treatment-of-diabetic-foot-ulcers/) - DOWNLOAD NOW Author: Prof Harikrishna KR Nair S.I.S. KMN MD FRCPI FCWCS FMSWCP CMIA CHM │ Wound Care Unit, Dept of Internal Medicine, Hospital Kuala Lumpur Aim: To determine the efficacy of continuous oxygen therapy in the treatment of previously non-healing diabetic foot ulcers (DFU) where the majority of patients had a history of infections - [The Efficacy of Continuous Topical Oxygen Therapy in the Treatment of Challenging Diabetic Foot Ulcers; A Case Series](https://www.natroxwoundcare.com/resource/the-efficacy-of-continuous-topical-oxygen-therapy-in-the-treatment-of-challenging-diabetic-foot-ulcers-a-case-series/) - Authors: Professor Dr. Harikrishna K. R. Nair, Dr Windy Cole, Dr Breda Cullen, Nick Howard, Dr Emma Woodmansey Presented at: GWC 2023, Malaysia Keywords: continuous oxygen therapy (cTOT), infection, prior amputation, NATROX® O₂ Summary: Case series examining the efficacy of continuous oxygen therapy (cTOT) in the treatment of previously non-healing diabetic foot ulcers (DFU) where - [IWGDF Guidelines Support Topical Oxygen Therapy (TOT)](https://www.natroxwoundcare.com/resource/iwgdf-guidelines-support-topical-oxygen-therapy-tot/) - Under the new guidelines, the IWGDF recommends clinicians consider using topical oxygen as an adjunct to Standard of Care for people with diabetic foot ulcers. - [Supplemental Oxygen Therapy in Wound Healing](https://www.natroxwoundcare.com/resource/supplemental-oxygen-therapy-in-wound-healing/) - Discover how the NATROX O2 randomized clinical trial addresses critical issues in DFU trial design. Gain insights for future advancements. - [Continuous Topical Oxygen Made Easy](https://www.natroxwoundcare.com/resource/continuous-topical-oxygen-made-easy/) - Unlock simplified continuous topical oxygen therapy with the NATROX O₂ Made Easy resource. Evidence-based insights & practical tips for optimal wound healing. - [WHS (Wound Healing Society) guidelines update: Diabetic foot ulcer treatment guidelines](https://www.natroxwoundcare.com/resource/whs-wound-healing-society-guidelines-update-diabetic-foot-ulcer-treatment-guidelines/) - Topical Oxygen Therapy (TOT) is recognised as the highest level of evidence (Level 1), showing increased healing and decreased time to heal. - [Combination therapy for a non-healing VLU](https://www.natroxwoundcare.com/resource/combination-therapy-for-a-non-healing-venous-leg-ulcer-vlu/) - Discover how a venous leg ulcer with a 3-year history achieved total wound closure using continuous topical oxygen therapy in combination with CAMPs. - [Impact of continuous Topical Oxygen Therapy on biofilm gene expression in a porcine tissue model](https://www.natroxwoundcare.com/resource/impact-of-continuous-topical-oxygen-therapy-on-biofilm-gene-expression-in-a-porcine-tissue-model/) - VIEW POSTER VIEW ARTICLE Introduction Oxygen has been shown to increase the susceptibility of biofilms to antibiotics through enhancing metabolism. Thus, the topic ‘‘Impact of continuous topical oxygen therapy on biofilm gene expression in a porcine tissue model” was chosen for the Top 8 poster category at the 19th meeting of the Diabetic Foot Study - [Impact of Continuous Topical Oxygen Therapy on Fluid Handling](https://www.natroxwoundcare.com/resource/ctot-impact-on-fluid-handling-in-vitro-model/) - Explore how continuous topical oxygen therapy supports healing in elderly patients with chronic radiation-induced wounds. Learn more about this groundbreaking approach. - [Impact of Continuous Topical Oxygen Therapy on Wound Moisture Levels](https://www.natroxwoundcare.com/resource/impact-of-ctot-on-wound-moisture-levels/) - Explore how continuous topical oxygen therapy supports healing in elderly patients with chronic radiation-induced wounds. Learn more about this groundbreaking approach. - [Expert Opinion in Support of TOT](https://www.natroxwoundcare.com/resource/new-expert-opinion-in-support-of-tot/) - A 2022 publication from the American Diabetes Association (ADA) presents a clinical compendia on the latest evidence-based therapies for diabetic foot ulcers (DFUs). Contributing authors include heavy hitters such as Andrew Boulton, MD, DSC (HON), FACP, FRCP, David Armstrong, DPM, MD, PhD, Magnus Löndahl, MD, PhD, and Robert Frykberg, DPM, MPH. Citation: Boulton, A.J.M., Armstrong, D.G., - [Consensus round table meeting: Clinical pathway for using TOT](https://www.natroxwoundcare.com/resource/consensus-round-table-meeting-clinical-pathway-for-using-topical-oxygen-therapy-in-practice/) - [Delphi Consensus on Guidelines for the Use of Topical Oxygen](https://www.natroxwoundcare.com/resource/delphi-consensus-on-guidelines-for-the-use-of-topical-oxygen/) - DOWNLOAD NOW View the article in the Journal of Wound Care READ FULL ARTICLE Key takeaways: TOT should be considered for delayed healing when other therapies have failed, or for ischemic ulcers Wound types likely to benefit: DFUs, VLUs, and ischemic ulcers. Abstract A growing body of evidence supports the use of topical oxygen therapy - [Health Technology Wales Guidance](https://www.natroxwoundcare.com/resource/health-technology-wales-guidance/) - Key takeaways: Routine adoption of cTOT, in addition to standard of care, increases complete wound healing and reduces wound area and time to healing compared to standard of care alone – and all with cost savings DOWNLOAD NOW Citation: Health Technology Wales (2022) Continuous topical oxygen therapy to treat people with chronic non-healing and complex - [A new algorithm for the management of diabetic foot ulcer: recommendations from Central and Eastern Europe](https://www.natroxwoundcare.com/resource/a-new-algorithm-for-the-management-of-diabetic-foot-ulcer-recommendations-from-central-and-eastern-europe/) - Clinical experts agree that “all hard-to-heal wounds are likely to benefit from Topical Oxygen Therapy (TOT), even after revascularization." - [Consensus on the Clinical Efficacy and Guidelines of Continuous Topical Oxygen Therapy for Wounds - JoWC LATAM Oct 2023](https://www.natroxwoundcare.com/resource/consensus-on-the-clinical-efficacy-and-guidelines-of-continuous-topical-oxygen-therapy-for-wounds-jowc-latam-oct-2023/) - This “expert consensus supports the efficacy and safety of continuous transdermal oxygen in the treatment of chronic and/or difficult-to-heal ulcers.” - [NATROX® O₂ – breakthrough in managing non-healing DFUs](https://www.natroxwoundcare.com/resource/natrox-oxygen-wound-therapy-a-breakthrough-in-the-management-of-non-healing-diabetic-foot-ulcers/) - Author: Prof. Harikrishna KR Nair, S.I.S, KMN, MD, FRCPI, FCWCS, FMSWCP, CMIA, CHMPresented at: Global Wound Conference (GWC) 2018Keywords: DFU Key points: NATROX® O₂ used on 8 previously non-healing diabetic wounds 7 out of 8 healed 95% reduction in the one that didn’t heal completely. Treatment duration was between 6 – 18 weeks DOWNLOAD NOW - [NATROX® O₂ case study – UK experience with DFUs](https://www.natroxwoundcare.com/resource/natrox-oxygen-wound-therapy-case-study-the-uk-experience/) - Dr. Jo McCardle, Podiatrist Consultant in the UK, walks you through her experience using NATROX® Oxygen Wound Therapy on DFU patients. She also examines the benefits of NATROX® for both patients and clinicians. NATROX® Oxygen Wound Therapy is an innovative but simple device that delivers 98% pure humidified oxygen directly to the wound bed, thus - [Topical oxygen therapy results in complete wound healing in diabetic foot ulcers](https://www.natroxwoundcare.com/resource/topical-oxygen-therapy-results-in-complete-wound-healing-in-diabetic-foot-ulcers/) - Wound Repair and Regeneration, 2016 VIEW ON WILEY LIBRARY Abstract: Diabetic foot ulcers (DFUs) are a significant problem in an ageing population. Fifteen percent of diabetics develop a DFU over their lifetime, which can lead to potential amputation. The 5-year survival rate after amputation is 31%, which is greater than the lifetime risk of mortality - [Dr. Lee presents: Continuous TOT - Improving Healing in Diabetic Foot](https://www.natroxwoundcare.com/resource/dr-lee-presents-continuous-topical-oxygen-therapy-improving-healing-in-the-diabetic-foot/) - Learn how Continuous Topical Oxygen Therapy, presented by Dr. Lee, improves healing outcomes for diabetic foot ulcers. Explore cutting-edge wound care insights with NATROX® O₂. - [Promoting Healing of Chronic Wounds Using cTOT in a Patient with Chronic Limb Threatening Ischaemia Having No Revascularisation Option](https://www.natroxwoundcare.com/resource/promoting-healing-of-chronic-wounds-using-continuous-topical-oxygen-therapy-in-a-patient-with-chronic-limb-threatening-ischaemia-having-no-revascularisation-option/) - Chronic limb threatening ischaemia (CLTI) is associated with mortality, limb amputation and impaired quality of life. - [The Use of cTOT in Combination with Cellular, Acellular and Matrix-like Products to Treat Complex, Chronic Wounds: a Retrospective Case Series](https://www.natroxwoundcare.com/resource/the-use-of-continuous-topical-oxygen-therapy-in-combination-with-cellular-acellular-and-matrix-like-products-to-treat-complex-chronic-wounds-a-retrospective-case-series/) - This poster investigates chronic wound progress when cTOT is used to optimize the wound environment prior to applying cellular, acellular and matrix-like products. - [Supporting the Patient Journey: The Use of Topical Oxygen Therapy in Chronic Wound Pain Management](https://www.natroxwoundcare.com/resource/patient-journey-using-topical-oxygen-therapy-in-chronic-wound-pain-management/) - VIEW THE ARTICLE The article discusses advancements in wound care management, emphasizing the importance of integrating patient-reported outcomes measures (PROMs) and patient-reported experience measures (PREMs) alongside traditional clinical metrics. Chronic wounds, which significantly affect patients’ quality of life, can lead to pain, social isolation, and decreased functional ability. The use of novel treatments like continuous - [Accelerated Healing with NATROX® O₂: Managing Late Radiation Tissue Injury Following Mohs Surgery](https://www.natroxwoundcare.com/resource/chronic-radiation-tissue-necrosis-wounds-continuous-topical-oxygen-therapy-supports-wound-healing-in-patients-of-advanced-age/) - Rejuvenate tissue health with NATROX® O₂. Explore a case series from WOUNDS journal highlighting accelerated healing and pain relief in late radiation tissue injury post-Mohs surgery. - [3 exciting results give you clinical confidence to recommend NATROX® O₂](https://www.natroxwoundcare.com/resource/3-exciting-results-give-you-clinical-confidence-to-recommend-natrox/) - Explore 3 compelling clinical results that provide confidence in recommending NATROX® O₂ Continuous Topical Oxygen Therapy for chronic wound healing. - [Anna's Story: Healing with NATROX® O₂ Continuous Topical Oxygen Therapy](https://www.natroxwoundcare.com/resource/annas-story/) - Discover Anna’s inspiring journey of recovery using NATROX® O₂ Continuous Topical Oxygen Therapy. See how chronic wound care innovations make a difference. - [Sally's Pain-Free Miracle: A NATROX® O₂ Testimonial at 91](https://www.natroxwoundcare.com/resource/sallys-natrox-o₂-testimonial/) - Meet Sally, a 91-year-old who defied pain with NATROX® O₂. Watch as she shares her journey from a non-healing leg ulcer to a life without pain and a healed wound. This testimonial unveils the miraculous transformation that continuous topical oxygen therapy brought to Sally's life. Dive into the transformative power of NATROX® O₂ and discover - [Challenging wounds, improving outcomes - Treatment of complex DFUs](https://www.natroxwoundcare.com/resource/challenging-wounds-improving-outcomes-treatment-of-complex-diabetic-foot-wounds-using-natrox-oxygen-wound-therapy/) - [The use of NATROX® O₂ topical oxygen therapy on patients with recalcitrant DFUs](https://www.natroxwoundcare.com/resource/the-use-of-topical-natrox-oxygen-wound-therapy-on-patients-with-recalcitrant-diabetic-foot-wounds/) - Authors: J. Boey, M.H. Koh, T.Y. Tang, T.T. ChongPresented at: Global Wound Conference (GWC) 2018 Key points: Case study on 2 patients Both have significant vascular disease Worst of the worst Dr Tang uses NATROX® O₂ to facilitate surgical closure DOWNLOAD NOW - [Oxygen Wound Therapy device: Continous flow of pure humidified oxygen for the treatment of infected wounds during antibiotic resistance](https://www.natroxwoundcare.com/resource/oxygen-wound-therapy-device-continous-flow-of-pure-humidified-oxygen-for-the-treatment-of-infected-wounds-during-antibiotic-resistance/) - Authors: Dr. Sonia Silvestrini, Antonella Leto, Cinzia Senesi, Aime Perungini, Alessio di Sano Presented at: EWMA 2019 DOWNLOAD NOW - [Delivery of oxygen to a liquid medium by a novel oxygen delivery device](https://www.natroxwoundcare.com/resource/delivery-of-oxygen-to-a-liquid-medium-by-a-novel-oxygen-delivery-device/) - [Julia's Story](https://www.natroxwoundcare.com/resource/julias-story/) - I am a 39-year-old, active female. I enjoy spending time in the water and tending to my sheep farm. Due to injury, I had a megaprosthesis implanted during limb sparing surgery. Unfortunately, it loosened twice in four years. In April 2019, I had to make the difficult decision to have my left leg amputated above - [Topical oxygen therapy used to improve wound healing in a large retrospective study of wounds of mixed aetiology](https://www.natroxwoundcare.com/resource/topical-oxygen-therapy-used-to-improve-healing-in-large-retrospective-study-of-wounds-of-mixed-aetiology/) - This 200-patient study demonstrated topically administered oxygen can increase healing in chronic wounds of all aetiologies. Topical oxygen was most effective in venous ulcers (VLUs), and achieved an average closure of 52% over the study period. Longer treatment times were associated with more effective wound healing, evidenced by average wound closures of 67.9%. Portable topical - [NATROX® O₂ radically improves patients’ lives](https://www.natroxwoundcare.com/resource/natrox-o₂-therapy-radically-improves-patients-lives/) - Case study of a 92-year old male patient with a painful non-healing mixed leg ulcer. After using NATROX® O₂ topical oxygen wound therapy, the patient experienced pain relief in the 1st week. His wound healed in 15 weeks, after having lived with this painful ulcer an astonishing 156 weeks (3 years). The attending clinician reported - [Topical Oxygen Therapy relieves pain from hard-to-heal leg ulcers and improves healing: a case series](https://www.natroxwoundcare.com/resource/topical-oxygen-treatment-relieves-pain-from-hard-to-heal-leg-ulcers-and-improves-healing-a-case-series/) - Journal of Wound Care, January 2022 Author: Jebril W, Nowak M, Palin L, Nordgren M, Bachar-Wikstrom E, Wikstrom JD. Keywords: analgesia, diabetes, dressing, HBOT, hard-to-heal leg ulcer, hyperbaric oxygen therapy, pain, topical continuous oxygen therapy, topical oxygen therapy, TCOT, TOT, ulcer, venous ulcer, wound, wound healing - [New Study Shows Substantial, Rapid Pain Relief Using NATROX® O₂](https://www.natroxwoundcare.com/resource/new-study-shows-substantial-rapid-pain-relief-using-natrox-o₂/) - [Healing Steps: Ricardo's Journey with NATROX® O₂](https://www.natroxwoundcare.com/resource/healing-steps-ricardos-journey-with-natrox-o₂/) - Witness the inspiring journey of Ricardo Medina, a 48-year-old street vendor from Barranquilla, Colombia. Diagnosed with diabetes mellitus and facing a severe neuropathic plantar ulcer with abscessed cellulitis, Ricardo's life took a positive turn with NATROX® O₂ continuous topical oxygen therapy. In this heartfelt testimonial, Ricardo shares how this pocket-sized, silent device became his constant - [Remote assessment and monitoring with advanced wound therapy to optimise clinical outcomes, access and resources](https://www.natroxwoundcare.com/resource/remote-assessment-and-monitoring-with-advanced-wound-therapy-to-optimise-clinical-outcomes-access-and-resources/) - Rural patients have limited access to wound care; however, this may be mitigated using a shared care approach of remote assessment and NATROX O2. - [NATROX® O₂ Topical Oxygen Therapy: Master Evidence Summary & Clinical Insights](https://www.natroxwoundcare.com/resource/natrox-o₂-master-evidence-summary/) - Discover the power of NATROX® O₂ with our comprehensive evidence summary. Learn why it's recommended by the ADA and IWGDF for diabetic foot ulcers. - [Managing Wound Pain: International Perspectives on Assessments, Challenges and Treatment Options](https://www.natroxwoundcare.com/resource/managing-wound-pain-international-perspectives-treatment-options/) - Explore expert insights on wound pain management, assessing challenges, and treatment strategies. Download the article for comprehensive international perspectives. - [Antimicrobial Resistance Stewardship in Wound Management](https://www.natroxwoundcare.com/resource/antimicrobial-resistance-stewardship-in-wound-management/) - Discover how the NATROX O2 randomized clinical trial addresses critical issues in DFU trial design. Gain insights for future advancements. - [A model for diabetic foot ulcer clinical trials on advanced therapies](https://www.natroxwoundcare.com/resource/a-model-for-diabetic-foot-ulcer-clinical-trials-on-advanced-therapies/) - Discover how the NATROX O2 randomized clinical trial addresses critical issues in DFU trial design. Gain insights for future advancements. - [Findings from an expert panel meeting on NATROX® O₂](https://www.natroxwoundcare.com/resource/findings-from-an-expert-panel-meeting-on-natrox-oxygen-wound-therapy/) - DOWNLOAD NOW Authors: Keith Harding, Karen Cross, Hanna Kaufman, Harikrishna K. Ragavan Nair, Gregory Schultz, Ibby Younis Wounds International, 2020 Citation: Harding, K, Cross, K., Kaufman, H., et al, 2020. Findings from an expert panel meeting on NATROX® Oxygen Wound Therapy. Wounds International, 11(1): 47-52. Keywords: compliance, concordance, oxygen therapy, pain relief, quality of healing A group - [Non-healing amputation wound](https://www.natroxwoundcare.com/resource/non-healing-amputation-wound/) - Author: Lin You Cheng Keywords: fast healing, quality of life, home care, collagen, alginate, never too old to heal Key points: Patient: 76-year-old male, 2nd + 3rd toe amputations. Tissue oxygenation plays a key role in healing. Non-healing post-amputation wound of 2nd and 3rd toe open for 6 months. Open 24 weeks, healed in 8 weeks. Previous dressings included - [Non-healing traumatic wound](https://www.natroxwoundcare.com/resource/non-healing-traumatic-wound/) - Author: Lin You Cheng Keywords: home care, quality of sleep, easy to use, no impact on lifestyle Key points: Patient: 76-year-old male, 24-week chronic lower leg wound (VLU) Portable device ideal for home care setting. Wound present for 6 months, healed in 5 weeks. The patient found it very user-friendly. Therapy was delivered even during sleep. No impact on - [Revitalizing Life: Bonnie's Journey with NATROX® O₂](https://www.natroxwoundcare.com/resource/revitalizing-life-bonnies-journey-with-natrox-o₂/) - Join us in Bonnie's transformative journey as she shares her healing experience with NATROX® O₂. Bonnie discovered a lifeline in topical oxygen therapy. - [Painful non-healing mixed leg ulcer](https://www.natroxwoundcare.com/resource/painful-non-healing-mixed-leg-ulcer/) - Case study by Malin Wilson, Dermatology Nurse, Helsingborg, Sweden. After 3 long years, this patient finally experienced pain relief in just 1 week using NATROX® O₂ topical oxygen wound therapy. His wound fully healed in 15 weeks of treatment. This case supports the usefulness of NATROX® O₂ for home care settings and how the therapy - [Holistic Approach to a Wound Care Patient](https://www.natroxwoundcare.com/resource/holistic-approach-to-a-wound-care-patient/) - Authors: Dr. Praveenan; S.Elangovan; Presented at: GWC 2023, Malaysia Keywords: cTOT, infection, prior amputation, NATROX® O₂ Summary: The presentation highlights a comprehensive approach to patient care for a multi-morbid individual diagnosed with diabetes mellitus, hypertension, gout, anemia, and ischemic heart disease. The focus is on a diagnostic and management process, including counselling for the patient - [Topical oxygen therapy for chronic wounds: a report on the potential of NATROX® a new device for delivering enriched oxygen to chronic wounds](https://www.natroxwoundcare.com/resource/topical-oxygen-therapy-for-chronic-wounds-a-report-on-the-potential-of-natrox-a-new-device-for-delivering-enriched-oxygen-to-chronic-wounds/) - Explore the clinical insights and preliminary studies showcasing the safety and efficacy of NATROX® O₂, a topical oxygen therapy for chronic wounds. Download the clinical resource PDF to learn more. - [TOT promotes the healing of chronic DFUs: pilot study](https://www.natroxwoundcare.com/resource/topical-oxygen-therapy-promotes-the-healing-of-chronic-diabetic-foot-ulcers-a-pilot-study/) - Title: Topical oxygen therapy promotes the healing of chronic diabetic foot ulcers: a pilot study Journal of Wound Care, 2017 Authors: P.D. Hayes, N. Alzuhir, G. Curran, I.M. Loftus Key points: 10 patients, with a mean ulcer duration of 43 weeks before treatment. By week 8, meal ulcer size had decreased by 51% 7 out of 10 ulcers - [NATROX® O₂ topical oxygen wound therapy: A vital element in wound healing](https://www.natroxwoundcare.com/resource/natrox-oxygen-wound-therapy-a-vital-element-in-wound-healing/) - DOWNLOAD NOW Author: Tang Tjun Yip, Borripatara Wongprachum, Ibby Younis Publication: Wounds Asia, 2019 Citation: Yip TT, Wongprachum B, Younis I. (2019) NATROX® Oxygen Wound Therapy: a vital element in wound healing. Wounds Asia, 10(1):44-7. Keywords: Acute wounds, chronic/complex wounds, DFU, NPWT, skin graft Key points: The impact of persistent hypoxia is presented in the top table. - [Topical Oxygen Therapy Shifts Microbiome Dynamics in Chronic Diabetic Foot Ulcers](https://www.natroxwoundcare.com/resource/topical-oxygen-therapy-shifts-microbiome-dynamics-in-chronic-diabetic-foot-ulcers/) - DOWNLOAD NOW Authors: Paul Hunter, BSc; Elisa Greco, MD; Karen Cross, MD, PhD; and Julie Perry, PhD Citation: Hunter, P., Greco, E., Cross, K., Perry, J., 2020. Topical oxygen therapy shifts microbiome dynamics in chronic diabetic foot ulcers. Wounds: a compendium of clinical research and practice, 32(3), 81–85. Keywords: microbiome, biofilm, diabetic foot ulcer, DFUs, - [Measuring the Effect of Continuous Topical Oxygen Therapy Case with Near Infrared Spectroscopy (NIRS)](https://www.natroxwoundcare.com/resource/enhancing-wound-healing-continuous-topical-oxygen-therapy-case-series/) - READ THE ARTICLE Overview In a new study published in Wounds (May 2024), Dr. Windy Cole and Dr. Emma Woodmansey explored the effectiveness of Continuous Topical Oxygen Therapy (cTOT) in treating chronic nonhealing wounds. The study, titled "Monitoring the Effect of Continuous Topical Oxygen Therapy With Near-Infrared Spectroscopy: A Pilot Case Series in Wound Healing", New case series on cTOT and near-infrared spectroscopy, reveals enhanced wound healing and tissue oxygenation in chronic wound patients. - [Topical Oxygen Therapy in Hard to Heal Wound - A Serial Case Study](https://www.natroxwoundcare.com/resource/topical-oxygen-therapy-in-hard-to-heal-wound-a-serial-case-study/) - This study aims to evaluate the efficacy of topical oxygen therapy in managing hard to heal chronic wounds. - [Percentage area reduction at week 4 as a prognostic indicator of complete healing in patients treated with standard of care: a post hoc analysis](https://www.natroxwoundcare.com/resource/percentage-area-reduction-at-week-4-as-a-prognostic-indicator-of-complete-healing-in-patients-treated-with-standard-of-care-a-post-hoc-analysis/) - Discover how the NATROX O2 randomized clinical trial addresses critical issues in DFU trial design. Gain insights for future advancements. - [Clinician Information Leaflet](https://www.natroxwoundcare.com/resource/clinician-information-leaflet/) - What's inside: Space for clinicians to write patient details and treatment to aid communication across care settings, plus: Hints & tips to ensure optimum application Reminders to reinforce with patients About the device QR code to watch the application video Easy visual instructions on how to apply the product What to expect during therapy Global - [MedTech Marvel: Harnessing the Healing Power of Oxygen](https://www.natroxwoundcare.com/resource/medtech-marvel-harnessing-the-healing-power-of-oxygen/) - Discover how NATROX® O₂ therapy revolutionizes wound care in an interview with Craig Kennedy, CEO of NATROX Wound Care. Download now for insights! - [Breaking Ground in Wound Healing: The Rise of Topical Oxygen Therapy](https://www.natroxwoundcare.com/resource/breaking-ground-in-wound-healing-the-rise-of-topical-oxygen-therapy/) - Discover valuable clinical insights from leading experts on how topical oxygen fills a key niche that has been missing in wound care. - [Quick Guide to Continuous Topical Oxygen Therapy (cTOT)](https://www.natroxwoundcare.com/resource/quick-guide-to-continuous-topical-oxygen-therapy-ctot/) - Discover the power of continuous topical oxygen therapy with our Quick Guide! Packed with evidence-based practices and updates on international standards, this resource is a must-have for healthcare professionals in wound care management. Download now for optimized patient outcomes! - [Top 3 reasons NATROX® O₂ receives 90% patient satisfaction](https://www.natroxwoundcare.com/resource/the-top-3-reasons-why-natrox-receives-90-patient-satisfaction-scores/) - Introduction: Transforming Chronic Wound Healing In this video, we'll help you discover the groundbreaking therapy that's transforming the way we heal chronic wounds. Frustrated with Traditional Therapies? Are you tired of dealing with wounds that just won't heal or keep coming back? Have traditional oxygen therapy systems left you and your patients frustrated? Introducing NATROX® - [Healthy feet poster](https://www.natroxwoundcare.com/resource/healthy-feet-poster/) - [Healthy feet postcard](https://www.natroxwoundcare.com/resource/healthy-feet-postcard/) - [Troubleshooting Guide for NATROX® O₂](https://www.natroxwoundcare.com/resource/troubleshooting-guide/) - This document is intended as a quick-and-easy guide to NATROX® O₂, providing clinicians with information on identifying and addressing potential issues. - [NATROX® O₂ application video (USA)](https://www.natroxwoundcare.com/resource/natrox-application-video/) - [Chronic wounds - the silent epidemic](https://www.natroxwoundcare.com/resource/chronic-wounds-the-silent-epidemic/) - [NATROX® O₂ self-application video](https://www.natroxwoundcare.com/resource/natrox-self-application-video/) - [Diabetes Awareness](https://www.natroxwoundcare.com/resource/diabetes-awareness/) - DOWNLOAD NOW - [4 Tests to Diagnose PAD (Peripheral Artery Disease)](https://www.natroxwoundcare.com/resource/4-tests-to-diagnose-pad-peripheral-artery-disease/) - Discover four common tests healthcare providers use to diagnose Peripheral Artery Disease (PAD), what the tests are, and what you can expect. We encourage you to learn more about PAD from the NHS, the American Heart Association, or the European Society of Cardiology (ESC). - [Innovating Wound Healing: Roundtable Talk on Continuous Topical Oxygen Therapy](https://www.natroxwoundcare.com/resource/innovating-wound-healing-roundtable-talk-on-continuous-topical-oxygen-therapy/) - Dive into the benefits of continuous topical oxygen therapy in wound care. Hear expert insights on patient considerations and therapy approaches in this webinar. - [Transforming Wound Care: Harnessing Continuous Topical Oxygen Therapy (cTOT) in Clinical Practice](https://www.natroxwoundcare.com/resource/transforming-wound-care-harnessing-continuous-topical-oxygen-therapy-ctot-in-clinical-practice/) - See Dr. Wahab's insights on topical oxygen therapy in wound care. She shares real-life case studies, explaining how integrating TOT enhances patient outcomes. - [Decoding Topical Oxygen Therapy & Wound Biofilms: Insights from Dr. Gregory Schultz, Biofilm Expert](https://www.natroxwoundcare.com/resource/decoding-topical-oxygen-therapy-amp-wound-biofilms-insights-from-dr-gregory-schultz-biofilm-expert/) - Discover the transformative role of oxygen in wound healing with Dr. Gregory Schultz. Gain insights into continuous topical oxygen for enhanced healing outcomes. - [Unlocking the Healing Power of Oxygen: Insights from Dr. Thomas Serena](https://www.natroxwoundcare.com/resource/unlocking-the-healing-power-of-oxygen-insights-from-dr-thomas-serena/) - Dr. Thomas Serena shares insights on oxygen's role in wound healing and new research on topical oxygen therapy's effectiveness in treating chronic wounds. - [NATROX® O₂ breakfast symposium at GWC 2019 Malaysia](https://www.natroxwoundcare.com/resource/natrox-breakfast-symposium-at-gwc-2019-in-kuala-lumpur/) - [NATROX® O₂ case study – Malaysian experience](https://www.natroxwoundcare.com/resource/natrox-oxygen-wound-therapy-case-study-the-malaysian-experience/) - Prof. Dr. Harikrishna K.R.Nair, Head Of Unit and President of the Malaysian Society of Wound Care Professionals, talks about his experience and results obtained adopting NATROX® Oxygen Wound Therapy. He also explores the Standard of Care in treating chronic wounds and the role of oxygen in wound healing. NATROX® O₂ topical oxygen wound therapy is - [NATROX® O₂ case study – Italian experience](https://www.natroxwoundcare.com/resource/natrox-oxygen-wound-therapy-case-study-the-italian-experience/) - Prof. E. Ricci, Contract Professor at the University of Turin and WUWHS Secretary, walks you through his clinical experience and the great results achieved with NATROX® O₂ topical oxygen wound therapy. NATROX® O₂ topical oxygen wound therapy is an innovative but simple device that delivers 98% pure humidified oxygen directly to the wound bed, thus - [Revolutionizing Wound Care: The Life-Changing Impact of NATROX® O₂ Topical Oxygen Wound Therapy](https://www.natroxwoundcare.com/resource/healthy-communities-healthy-people/) - In a communications initiative with the new NHS alliance and ITN Productions, NATROX® O₂ was featured in their campaign to promote "Healthy Communities, Healthy People." Discover the groundbreaking innovation transforming wound care with NATROX® O₂, a form of wearable oxygen therapy. Developed by Inotec AMD, a spin-off company from the University of Cambridge, this portable - [The story behind NATROX® O₂](https://www.natroxwoundcare.com/resource/the-story-behind-natrox-oxygen-wound-therapy/) - Listen to our founder, Mel Vinton, tell the story that brought NATROX® O₂ topical oxygen wound therapy to life. - [NATROX® O₂ - the “holy grail” in wound care](https://www.natroxwoundcare.com/resource/natrox-oxygen-wound-therapy-the-holy-grail-in-wound-care/) - The executive board members explain why they believe in NATROX® O₂ toical oxygen wound therapy NATROX® O₂ topical oxygen wound therapy is an innovative but simple device that generates and delivers oxygen directly to the wound bed, thus stimulating and improving wound healing. As NATROX® O₂ is battery-operated, completely portable and totally silent, this active - [The Importance of NATROX® O₂](https://www.natroxwoundcare.com/resource/the-importance-of-natrox-oxygen-wound-therapy-2/) - In this video, some members of the NATROX® team explain the importance of NATROX® O₂ and the benefits and great impact it has on people's life. NATROX® O₂ topical oxygen wound therapy is an innovative but simple device that generates and delivers oxygen directly to the wound bed, thus stimulating and improving wound healing. As - [From Wound to Marathon: Mr. Christie's Healing Journey with NATROX® O₂](https://www.natroxwoundcare.com/resource/mr-christie-jacobs-natrox-o₂-testimonial/) - Witness the inspiring journey of 80-year-old athlete Mr. Christie Jacobs, who triumphed over a chronic Achilles tendon wound with NATROX® O₂ continuous topical oxygen therapy. After enduring three years of pain and the looming threat of amputation, Mr. Christie shares how NATROX® O₂ transformed his life. Now, healed and preparing for his next marathon, his - [NATROX® Wound Care Recognised as a Top MedTech Provider 2023](https://www.natroxwoundcare.com/resource/natrox-wound-care-recognised-as-a-top-medtech-provider-2023/) - DOWNLOAD NOW - [Delivery of oxygen to a liquid medium](https://www.natroxwoundcare.com/resource/delivery-of-oxygen-to-a-liquid-medium/) - [Battling the biofilm in chronic wounds: NATROX® O₂ shifts biofilm](https://www.natroxwoundcare.com/resource/battling-the-biofilm-in-chronic-wounds-natrox-oxygen-wound-therapy-shifts-the-bacteria-biofilm-in-chronic-wounds/) - [Oxygen therapies for wound healing: EWMA findings and recommendations](https://www.natroxwoundcare.com/resource/oxygen-therapies-for-wound-healing-ewma-findings-and-recommendations/) ## Staff - [Sandy Fliri-Marx](https://www.natroxwoundcare.com/staff/sandy-fliri-marx/) - Director, Human Resources - [David Fernández](https://www.natroxwoundcare.com/staff/david-fernandez/) - International Sales Director - [Gordie Nye](https://www.natroxwoundcare.com/staff/gordie-nye/) - Advisor - [Michael Clancy](https://www.natroxwoundcare.com/staff/michael-clancy/) - Interim CEO - [Pierre Socha](https://www.natroxwoundcare.com/staff/pierre-socha/) - Non-Executive Director - [Dr. Windy Cole, DPM, CWSP, FAPWH](https://www.natroxwoundcare.com/staff/dr-windy-cole-dpm-2/) - Director, Global Medical Affairs - [Stefanie Brown Hawkins](https://www.natroxwoundcare.com/staff/stefanie-brown-hawkins/) - Chief Financial Officer - [Nancy Stahulak](https://www.natroxwoundcare.com/staff/nancy-stahulak/) - VP, U.S. Sales & Global Marketing - [John Adam](https://www.natroxwoundcare.com/staff/john-adam/) - COO ## Videos - [What to Expect](https://www.natroxwoundcare.com/videos/what-to-expect/) - Dr. Aliza Lee, DPM, MS, ABPM, Director of Podiatric Medical Education, Staff Podiatrist, and Clinical Research Investigator ( at the V.A. Hospital in Salem, Virginia presents her latest 12-week study on 8 patients exploring the combined use of NATROX® O₂ with an advanced digital platform using Telehealth to understand the clinical benefits. Results showed: • ## Events - [PVA Healthcare Summit](https://www.natroxwoundcare.com/events/pva-healthcare-summit/) - [Small Business VA Industry Days - Multiple Locations](https://www.natroxwoundcare.com/events/small-business-va-industry-day/) - [SAWC Fall 2026](https://www.natroxwoundcare.com/events/sawc-fall/) - NATROX® Wound Care is exhibiting at SAWC Fall 2026 to showcase the innovative NATROX O₂ continuous topical oxygen therapy for chronic wounds. ## Categories - [Uncategorized](https://www.natroxwoundcare.com/category/uncategorized/) - [Staff Member](https://www.natroxwoundcare.com/category/corporate/staff-member/) - [Board Member](https://www.natroxwoundcare.com/category/corporate/board-member/) - [Clinical](https://www.natroxwoundcare.com/category/clinical/) - [Corporate](https://www.natroxwoundcare.com/category/corporate/) - [Events](https://www.natroxwoundcare.com/category/events/) - [Clinical Advisory Board](https://www.natroxwoundcare.com/category/corporate/clinical-advisory-board/) ## Tags - 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[Diabetic Foot Ulcer (DFU)](https://www.natroxwoundcare.com/tag/diabetic-foot-ulcer-dfu/) - [Durability](https://www.natroxwoundcare.com/tag/durability/) - [Ischemic Ulcer](https://www.natroxwoundcare.com/tag/ischemic-ulcer/) - [Mixed Leg Ulcer](https://www.natroxwoundcare.com/tag/mixed-leg-ulcer/) - [Pain](https://www.natroxwoundcare.com/tag/pain/) - [Phlebostatic Ulcer](https://www.natroxwoundcare.com/tag/phlebostatic-ulcer/) - [Post-Mastectomy Wound](https://www.natroxwoundcare.com/tag/post-mastectomy-wound/) - [Pressure Injury/Pressure Ulcer](https://www.natroxwoundcare.com/tag/pressure-injury-pressure-ulcer/) - [Radiation Tissue Wound](https://www.natroxwoundcare.com/tag/radiation-tissue-wound/) - [Surgical Wound Dehiscence (SWD)](https://www.natroxwoundcare.com/tag/surgical-wound-dehiscence-swd/) - [Trauma Wound](https://www.natroxwoundcare.com/tag/trauma-wound/) - [Venous Leg Ulcer (VLU)](https://www.natroxwoundcare.com/tag/venous-leg-ulcer-vlu/) - [Limb Salvage](https://www.natroxwoundcare.com/tag/limb-salvage/) - 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[Maxillofacial Osteoradionecrosis](https://www.natroxwoundcare.com/tag/maxillofacial-osteoradionecrosis/) - [Atypical Wound](https://www.natroxwoundcare.com/tag/atypical-wound/)