New Expert Opinion in Support of TOT

A 2022 publication from the American Diabetes Association (ADA) presents a clinical compendia on the latest evidence-based therapies for diabetic foot ulcers (DFUs).

Contributing authors include heavy hitters such as Andrew Boulton, MD, DSC (HON), FACP, FRCP, David Armstrong, DPM, MD, PhD, Magnus Löndahl, MD, PhD, and Robert Frykberg, DPM, MPH.

Citation: Boulton, A.J.M., Armstrong, D.G., Löndahl, M., et al., 2022. New Evidence-Based Therapies for Complex Diabetic Foot Wounds. ADA Clinical Compendia, pp.1–23. Available at: [Accessed 1 July 2022].

Worth noting is the author’s summary of the proven benefits of TOT: “In 2021, an expert consensus panel provided treatment guidelines for [TOT] and supported its use in clinical practice. It is anticipated that future evidence-based clinical practice guidelines will similarly recognize the proven benefits of TOT in healing chronic DFUs and establish recommendations for its use.”

Topical oxygen therapy has proven benefits in healing chronic diabetic foot ulcers. The evidence supporting the efficacy of TOT can no longer be disputed.

Read the full compendia published by the American Diabetes Association: