The Efficacy of Continuous Topical Oxygen Therapy in the Treatment of Challenging Diabetic Foot Ulcers; A Case Series

Authors: Professor Dr. Harikrishna K. R. Nair, Dr Windy Cole, Dr Breda Cullen, Nick Howard, Dr Emma Woodmansey

Presented at: GWC 2023, Malaysia

Keywords: continuous oxygen therapy (cTOT), infection, prior amputation, NATROX® O₂


Case series examining the efficacy of continuous oxygen therapy (cTOT) in the treatment of previously non-healing diabetic foot ulcers (DFU) where the majority of patients had a history of infections and prior amputations indicative of the severity and difficulty in healing.

Results showed:

  • a mean wound area reduction of 78%
  • 13 patients healed
  • the benefits of cTOT as an adjunctive therapy to progress hard-to-heal wounds previously stagnating with SoC.