Key Information

• Explains how the physiological changes in patients with spinal cord injuries (SCI) affect wound healing.
• Presents evidence showing how continuous topical oxygen therapy (cTOT) with NATROX® O₂ may help.
• Provides instructions on how to order.

References

1. Rappl LM. (2008) Physiological changes in tissues denervated by spinal cord injury tissues and possible effects on wound healing. Int Wound J, 5(3):435-44.
2. Younis I. (2020). Role of oxygen in wound healing. J Wound Care, 29(Sup5b):S4–S10.
3. Holzer-Geissler J, Schwingenschuh S, Zacharias M, et al. (2022) The Impact of Prolonged Inflammation on Wound Healing. Biomedicines, 10:856.
4. Kaufman H, Gurevich M, Tamir E, et al. (2018) Topical oxygen therapy stimulates healing in difficult, chronic wounds: a tertiary centre experience. J Wound Care, 27(7) 426-33.
5. Yu J, Lu S, McLaren AM, et al. (2016) Topical oxygen therapy results in complete wound healing in diabetic foot ulcers. Wound Repair Regen, 24:1066-72.
6. Cole W. (2020) The Use of a Topical Oxygen Therapy System to Promote Healing in Chronic Wounds. [Poster] SAWC Fall: Las Vegas. Link.
7. Lee, A. (2023) Barriers Eliminated: An Advanced Digital Wound Platform Combined with a Continuous Topical Oxygen Therapy System Improves Access, Saves Time, and Decreases Wound Size in Complex Diabetic Patients. [Poster] SAWC Spring: National Harbor. Link.
8. Sen CK. (2009) Wound Healing Essentials: Let There Be Oxygen. Wound Repair Regen, 17(1):6.
9. Al-Jalodi O, Kupcella M, Breisinger K, et al. (2022) A multicenter clinical trial evaluating the durability of diabetic foot ulcer healing in ulcers treated with topical oxygen and standard of care versus standard of care alone 1 year post healing. Int Wound J, 19(7):1-5.
10. Ball C, Jones H, Thomas H, et al. (2024) Impact of continuous Topical Oxygen Therapy on biofilm gene expression in a porcine tissue model. [Poster presentation] SAWC Spring: Orlando. Link.
11. Cole W, Woodmansey E. (2024) Antimicrobial Resistance and Stewardship in Wound Management. Podiatry Management, 2024 August:73-88.
12. Non-healing pressure injury. [Case study] Link.