New Evidence in Support of Topical Oxygen Therapy (TOT)

A new publication by the  presents the latest evidence-based therapies for diabetic foot ulcers (DFUs). Contributing authors include heavy hitters such as Prof. Andrew Boulton, MD, DSC (HON), FACP, FRCP, Prof. David Armstrong DPM, MD, PhD, Dr. Magnus Löndahl MD, PhD, and Robert Frykberg DPM, MPH.

They review the most recently published evidence-based data concerning topical oxy­gen therapies in addition to looking at future treatment approaches in the development pipeline, as well as the emerging role of wearable technologies.

Throughout the compendia, the authors present their view of current and forthcoming treatment options and iden­tify areas worthy of additional research in the years ahead.

Worth noting is their summary of the proven benefits of TOT:

“In 2021, an expert consensus panel provided treatment guidelines for [TOT] and supported its use in clinical practice. It is anticipated that future evidence-based clinical practice guidelines will similarly recognize the proven benefits of TOT in healing chronic DFUs and establish recommendations for its use.”¹

Read the full publication on the American Diabetes Association website

REFERENCE: 1. Andrew J.M. Boulton, et al, 2022. New Evidence-Based Therapies for Complex Diabetic Foot Wounds. ADA Clinical Compendia 22 February 2022; 2022 (2): 1–23. Available at: [Accessed 1 July 2022].