TOT promotes the healing of chronic DFUs: pilot study

Title: Topical oxygen therapy promotes the healing of chronic diabetic foot ulcers: a pilot study

Journal of Wound Care, 2017

Authors: P.D. Hayes, N. Alzuhir, G. Curran, I.M. Loftus

Key points:

  • 10 patients, with a mean ulcer duration of 43 weeks before treatment.
  • By week 8, meal ulcer size had decreased by 51%
  • 7 out of 10 ulcers were in a healing trajectory.
  • 1 ulcer present for 56 weeks healed completely.
  • A 2-year-old ulcer was reduced by more than 50%
  • A third ulcer, present for 88 weeks was down to 10% of its original size by the end of the 8-week study.
  • Trend toward reduction in pain, and the device was extremely well tolerated.
  • Practical advantages over hyperbaric oxygen therapy due to continuous oxygen delivery, ease of use, safety, and lower cost.
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